From: <Saved by Windows Internet Explorer 7>
Subject: Actions of Alcohol on the Brain
Date: Sat, 23 Feb 2008 11:43:47 -0500
MIME-Version: 1.0
Content-Type: multipart/related;
	type="multipart/alternative";
	boundary="----=_NextPart_000_001C_01C87611.59ACFD50"
X-MimeOLE: Produced By Microsoft MimeOLE V6.00.2900.3198

This is a multi-part message in MIME format.

------=_NextPart_000_001C_01C87611.59ACFD50
Content-Type: image/gif
Content-Transfer-Encoding: base64
Content-Location: http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001_files/buttons.gif
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------=_NextPart_000_001C_01C87611.59ACFD50
Content-Type: application/octet-stream
Content-Transfer-Encoding: quoted-printable
Content-Location: http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001_files/script.js


function LoadSld( slideId )
{
	if( !g_supportsPPTHTML ) return
	if( slideId )
		parent.SldUpdated(slideId)
	g_origSz=3DparseInt(SlideObj.style.fontSize)
	g_origH=3DSlideObj.style.posHeight
	g_origW=3DSlideObj.style.posWidth
	g_scaleHyperlinks=3D(document.all.tags("AREA").length>0)
	if( g_scaleHyperlinks )
		InitHLinkArray()
	if( g_scaleInFrame||(IsWin("PPTSld") && parent.IsFullScrMode() ) )
		document.body.scroll=3D"no"
	_RSW()
	if( IsWin("PPTSld") && parent.IsFullScrMode() )	{
		document.oncontextmenu=3Dparent._CM;
		self.focus()
	}
}
function MakeSldVis( fTrans )=20
{
	fTrans=3DfTrans && g_showAnimation
	if( fTrans )
	{
		if( g_bgSound ) {
			idx=3Dg_bgSound.indexOf(",");
			pptSound.src=3Dg_bgSound.substr( 0, idx );
			pptSound.loop=3D -(parseInt(g_bgSound.substr(idx+1)));
		}
		SlideObj.filters.revealtrans.Apply()
	}
	SlideObj.style.visibility=3D"visible"
	if( fTrans )
		SlideObj.filters.revealtrans.Play()
}
function MakeNotesVis()=20
{
	if( !IsNts() ) return false=20
	SlideObj.style.display=3D"none"
	nObj =3D document.all.item("NotesObj")
	parent.SetHasNts(0)
	if( nObj ) {=20
		nObj.style.display=3D""
		parent.SetHasNts(1)
	}
	return 1
}
function Redirect( frmId,sId )
{
	var str=3Ddocument.location.hash,idx=3Dstr.indexOf('#')
	if(idx>=3D0) str=3Dstr.substr(1);
	if( window.name !=3D frmId && ( sId !=3D str) ) {
		obj =3D document.all.item("Main-File")
		window.location.href=3Dobj.href+"#"+sId
		return 1
	}
	return 0
}
function HideMenu() { if( frames["PPTSld"] && =
PPTSld.document.all.item("ctxtmenu") && =
PPTSld.ctxtmenu.style.display!=3D"none" ) { =
PPTSld.ctxtmenu.style.display=3D'none'; return true } return false }
function IsWin( name ) { return window.name =3D=3D name }
function IsNts() { return IsWin("PPTNts") }
function IsSldOrNts() { return( IsWin("PPTSld")||IsWin("PPTNts") ) }
function SupportsPPTAnimation() { return( navigator.platform =3D=3D =
"Win32" && navigator.appVersion.indexOf("Windows")>0 ) }
function SupportsPPTHTML()
{
	var appVer=3Dnavigator.appVersion, msie=3DappVer.indexOf("MSIE "), =
ver=3D0
	if( msie >=3D 0 )
		ver=3DparseFloat( appVer.substring( msie+5, appVer.indexOf(";",msie) ) =
)
	else
		ver=3DparseInt(appVer)

	return( ver >=3D 4 && msie >=3D 0 )
}
var MHTMLPrefix =3D CalculateMHTMLPrefix();=20
function CalculateMHTMLPrefix()
{
	if ( document.location.protocol =3D=3D 'mhtml:') {=20
		href=3Dnew String(document.location.href)=20
		Start=3Dhref.indexOf('!')+1=20
		End=3Dhref.lastIndexOf('/')+1=20
		if (End < Start)=20
			return href.substring(0, Start)=20
		else=20
		return href.substring(0, End)=20
	}
	return '';
}

function _RSW()
{
	if( !g_supportsPPTHTML || IsNts() ||
	  ( !g_scaleInFrame && (( window.name !=3D "PPTSld" ) || =
!parent.IsFullScrMode()) ) )
		return

	cltWidth=3Ddocument.body.clientWidth
	cltHeight=3Ddocument.body.clientHeight
	factor=3D(1.0*cltWidth)/g_origW
	if( cltHeight < g_origH*factor )
		factor=3D(1.0*cltHeight)/g_origH

	newSize =3D g_origSz * factor
	if( newSize < 1 ) newSize=3D1

	s=3DSlideObj.style
	s.fontSize=3DnewSize+"px"
	s.posWidth=3Dg_origW*factor
	s.posHeight=3Dg_origH*factor
	s.posLeft=3D(cltWidth-s.posWidth)/2
	s.posTop=3D(cltHeight-s.posHeight)/2

	if( g_scaleHyperlinks )
		ScaleHyperlinks( factor )
}

function _KPH()
{=20
  if( IsNts() ) return;

  if( !parent.IsFramesMode() && event.keyCode =3D=3D 27 && =
!parent.HideMenu() )
    parent.window.close( self );
  else if( event.keyCode =3D=3D 32 )
  {
    if( window.name =3D=3D "PPTSld" )
      parent.PPTSld.DocumentOnClick();
    else
      parent.GoToNextSld();
  }
}

function PlaySound( href, loop ){
	href=3D unescape(href);
	if( window.event ) window.event.cancelBubble =3D true;
	pptSound.src =3D href;
	pptSound.loop =3D loop ? -1 : 0;
}
var AE_NONE =3D 0, AE_DIM =3D 1, AE_HIDE =3D 2, AE_HIDEIMDTLY =3D 3, =
LONG_INTERVAL =3D 10, SHORT_INTERVAL =3D 5, g_curAnim =3D null, g_vml =
=3D 0;
function ParseAnimations(){
	nr =3D document.all.tags("DIV").length;
	while(nr > 0) {
		rObj =3D document.all.tags("DIV").item(--nr);
		if(rObj.style.cssText !=3D null) {
			build =3D rObj.style.cssText.indexOf("mso-build");
			if(build >=3D 0)
				AddAnimation(rObj);
		}
	}
	if(g_autoTrans){
		totT=3D0, autoAnims=3D0;
		rAnims=3Dg_animManager.m_anims;
		nBuilds=3Dg_animManager.m_numBuilds;
		for(x=3DnBuilds;x>0;x--)
		if(-1 !=3D rAnims[x].m_secs){
			totT+=3DrAnims[x].m_secs;
			autoAnims++;
		}
		time=3Dg_transSecs-totT;
		if(time<0) time=3D0;
		time=3Dtime/(nBuilds-autoAnims+1);
		for(x=3DnBuilds;x>0;x--)
			if(-1 =3D=3D rAnims[x].m_secs)
				rAnims[x].m_secs=3Dtime;
	}
}
function AddAnimation(rObj){
	a =3Dnew Animation();
	a.m_obj =3DrObj;
	a.m_oldc =3DrObj.color;
	GetVal=3DrObj.style.getAttribute;
	var t;
	if( t=3DGetVal("mso-build") ) a.m_build=3Dt-0;
	if( t=3DGetVal("mso-build-after-action") ) a.m_aAct=3Dt-0;
	if( t=3DGetVal("mso-build-after-color") ) a.m_oldc=3Dt;
	if( t=3DGetVal("mso-build-auto-secs") ) a.m_secs=3Dt-0;
	if( t=3DGetVal("mso-build-avi") ) a.m_video=3Dt;
	if( t=3DGetVal("mso-build-dual-id") ) a.m_dId=3Dt;
	if( t=3DGetVal("mso-build-order") ) a.m_order=3Dt-0;
	if( t=3DGetVal("mso-build-sound-name") ) a.m_sound=3Dt;

	g_animManager.AddAnimation(a);
}
function ShowVGXObj(rObj){
	vmlId=3Dnull,ImgTag=3Dnull;
	curObj=3DrObj;
	sObj =3Ddocument.all.item("SlideObj");
	while(null =3D=3D ImgTag && null !=3D curObj && sObj !=3D curObj){
		ImgTag =3DcurObj.children.tags("IMG").item(0);
		curObj =3D(curObj.parentElement.tagName =3D=3D "DIV") ? =
curObj.parentElement : null
	}
	if(null !=3DImgTag)
		vmlId =3DImgTag.getAttribute("v:shapes");
	if(null !=3DvmlId) {
		idx =3DvmlId.indexOf(",");
		if(idx > 0) vmlId =3DvmlId.substr(0, idx);
		vgxObj =3Ddocument.all.item(vmlId);
		if((null !=3D vgxObj) && (null !=3D vgxObj.parentElement) && =
(vgxObj.parentElement.style.display !=3D "none")){
			vgxObj.parentElement.style.visibility =3D "visible";
			ImgTag.style.visibility =3D "hidden";
		}
		else
			rObj.style.visibility =3D "visible";
	}
}
function AnimationManager(){
	t=3Dthis;
	t.m_anims=3Dnew Array();
	t.m_numBuilds=3D0;
	t.m_activeObj=3Dnull;
	t.m_curBuild=3D1;
	t.m_timer=3D-1;
	t.m_objToHide=3Dnull;
	t.m_objToDim=3Dnull;
	t.m_colorToDim=3D-1;
	t.m_isPlaying=3D0;
	t.m_autoTimer=3D-1;
	t.Peek=3DAM_Peek;
	t.Next=3DAM_Next;
	t.Previous=3DAM_Previous;
	t.AddAnimation=3DAM_AddAnimation;
	t.ShowShapes=3DAM_ShowShapes;
	t.Swap=3DAM_Swap;
}
function AM_ShowShapes(){
	for(x=3Dthis.m_numBuilds; x>0; x--){
		if(g_vml)
			ShowVGXObj(this.m_anims[x].m_obj);
		aObj =3Dthis.m_anims[x].m_obj;
		if(aObj)
			aObj.style.visibility =3D "visible";
	}
	this.m_numBuilds =3D0;
}
function AM_Swap(cur){
	rList =3Dthis.m_anims;
	t =3DrList[cur+1];
	rList[cur+1] =3DrList[cur];
	rList[cur] =3Dt;
}
function AM_AddAnimation(a){
	this.m_anims[++this.m_numBuilds] =3D a;
	this.m_curBuild =3Dthis.m_numBuilds;
	cur =3Dthis.m_numBuilds;
	if(a.m_order > 0){
		while(cur-- > 1 && Math.abs(this.m_anims[cur+1].m_order) > =
Math.abs(this.m_anims[cur].m_order))
			this.Swap(cur);
	}
	else {
		while(cur-- > 1 && Math.abs(this.m_anims[cur+1].m_order) >=3D =
Math.abs(this.m_anims[cur].m_order))
			this.Swap(cur);
	}
}
function AM_Peek(){
	if(g_animManager.m_curBuild > 0 && 0 < g_animManager.m_numBuilds) {
		secs =3Dg_animManager.m_anims[g_animManager.m_curBuild].m_secs;
		if(secs !=3D -1)
			g_animManager.m_autoTimer =3D window.setTimeout("_DocAction()", =
secs);
	}
	else if(1 =3D=3D g_autoTrans && IsWin("PPTSld") && =
!parent.IsFramesMode()){
		setTimeout("parent.GoToNextSld()", g_transSecs);
	}
}
function AM_Next(){
	if(0 =3D=3D this.m_numBuilds || (g_curAnim !=3D null)) return 0;=20
	success=3D0;
	if(this.m_autoTimer !=3D -1)
		window.clearTimeout(this.m_autoTimer);
	if(this.m_objToHide !=3D null)
		this.m_objToHide.style.visibility =3D "hidden";
	if(this.m_objToDim !=3D null) {
		nr =3D document.all.length;
		while(nr-- > 0) {
			rObj =3Ddocument.all.item(nr);
			if(this.m_objToDim.contains(rObj))
				rObj.style.color =3D this.m_colorToDim;
		}
	}
	if(this.m_curBuild > 0) {
		this.m_activeObj =3Dthis.m_anims[this.m_curBuild--];
		this.m_activeObj.Start();
		success =3D1;
	}
	return success;
}
function AM_Previous(){
	if((null =3D=3D g_curAnim) && (this.m_curBuild <=3D this.m_numBuilds)) =
{
		this.m_curBuild++;
		var animObj =3D this.m_anims[this.m_curBuild];
		if(this.m_curBuild >=3D 1)
			animObj.m_obj.style.visibility =3D "hidden";
	}
}
function InitBuildEffects(){
	g_animManager =3Dnew AnimationManager();
	ParseAnimations();
	isFullScreen =3D(window.name =3D=3D "PPTSld") && =
!parent.IsFramesMode();
	if(!g_showAnimation || (isFullScreen && parent.IsSldVisited()))
		g_animManager.ShowShapes();
	else if(!g_hasTrans)
		g_animManager.Peek();
	if(isFullScreen && !g_isKiosk)
		parent.SetSldVisited();
}
function Animation(){
	t=3Dthis;
	t.m_obj=3D0;
	t.m_build=3D0;
	t.m_dId=3D"";
	t.m_aAct=3D0;
	t.m_secs=3D-1;
	t.m_order=3D0;
	t.m_sound=3D"";
	t.m_oldc=3D0;
	t.m_video=3D"";
	t.m_animObj=3D0;=20
	t.m_timer=3D-1;
	t.m_steps=3D0;
	t.m_finalL=3D0;
	t.m_finalT=3D0;
	t.m_finalW=3D0;
	t.m_finalH=3D0;
	t.Start=3DA_Start;
	t.End=3DA_End;
	t.Animate=3DA_Animate;
	t.SetupMove=3DA_SetupMove;
	t.DoMove=3DA_DoMove;
	t.DoSpiral=3DA_DoSpiral;
	t.DoSwivel=3DA_DoSwivel;
	t.DoInplace=3DA_DoInplace;
}
function TickHandler(){
	if(null !=3D g_curAnim) g_curAnim.Animate();
}
function GetAnimClass(dir){
	if(dir > 99) return 7;=20
	else if(dir > 28) return 5;=20
	else if(dir =3D=3D 27) return 4;=20
	else if(dir =3D=3D 28) return 3;=20
	else if((dir >=3D 12) && (dir < 16))return 2;=20
	else return 1;=20
}
function GetSteps(dir){
	animClass =3DGetAnimClass(dir);
	if(animClass =3D=3D 5 || animClass =3D=3D 7) return 1;=20
	res=3D12;
	if(animClass >=3D 2 && animClass <=3D 4) res =3D 50;
	if(SlideObj.style.backgroundImage !=3D "") res /=3D 2;
	return res;
}
function A_Start(){
	g_curAnim =3D this;
	this.SetupMove();
	if(this.m_sound)
		PlaySound(this.m_sound, false);
	animClass =3DGetAnimClass(this.m_build);
	if(5 =3D=3D animClass)
		this.DoInplace();
	else {
		this.m_animObj.style.visibility =3D "visible";
		time =3D 0;
		if(7 =3D=3D animClass) { // Appear and flash
			switch(this.m_build) {
				case 100: time =3D 300; break;
				case 101:
				case 200: time =3D 500; break;
				case 102: time =3D 1000; break;
			}
			if(this.m_build < 200)
				this.m_aAct =3D AE_HIDEIMDTLY;
		}
		else
			time =3D(animClass % 2 =3D=3D 0) ? LONG_INTERVAL : SHORT_INTERVAL;
		this.m_timer =3Dwindow.setInterval("TickHandler()", time);
	}
}
function A_End(){
	window.clearInterval(this.m_timer);
	if(this.m_video !=3D "")
		PlayMedia(this.m_video);
	rStyle =3D this.m_obj.style;
	if(this.m_dId =3D=3D ""){
		rStyle.pixelLeft =3Dthis.m_finalL;
		rStyle.pixelTop =3Dthis.m_finalT;
		rStyle.pixelWidth	=3Dthis.m_finalW;
		rStyle.pixelHeight =3Dthis.m_finalH;
	}
	else {
		if(this.m_aAct !=3D AE_HIDEIMDTLY)
			rStyle.visibility =3D "visible";
		this.m_animObj.style.visibility =3D "hidden";
	}
	switch(this.m_aAct){
		case AE_NONE:=20
			if(g_vml)
				ShowVGXObj(this.m_obj);
			break;
		case AE_DIM:
			if(g_vml)
				ShowVGXObj(this.m_obj);
			g_animManager.m_objToDim	=3Dthis.m_obj;
			g_animManager.m_colorToDim	=3Dthis.m_oldc;
			break;
		case AE_HIDE:
			g_animManager.m_objToHide	=3Dthis.m_obj;
			break;
		case AE_HIDEIMDTLY:
			rStyle.visibility =3D"hidden";
			break;
	}
	if(this.m_dId !=3D "")
		this.m_animObj.style.visibility =3D"hidden";
	if(!g_animManager.m_isPlaying){
		g_curAnim =3D null;
		this.m_obj =3D null;
		g_animManager.Peek();
	}
}
function A_Animate(){
	switch(GetAnimClass(this.m_build)) {
		case 1:
		case 2: this.DoMove();	break;
		case 3: this.DoSpiral();	break;
		case 4: this.DoSwivel();	break;
	}
	if(--this.m_steps =3D=3D 0)=20
		this.End();
}
function A_SetupMove(){
	dir =3Dthis.m_build;
	this.m_steps =3DGetSteps(dir);
	rObj =3Dthis.m_dId !=3D "" ? document.all.item(this.m_dId) : =
this.m_obj;
	this.m_animObj =3DrObj;
	offsetL=3D0;
	offsetT=3D0;
	parentObj=3DrObj.parentElement;
	while(parentObj.tagName !=3D "BODY" && parentObj.id !=3D "SlideObj"){
		offsetL	+=3DparentObj.offsetLeft;
		offsetT	+=3DparentObj.offsetTop;
		parentObj =3DparentObj.parentElement;=20
	}
	rStyle =3D rObj.style;
	this.m_finalL =3DsLeft =3DrStyle.pixelLeft;
	this.m_finalT =3DsTop =3DrStyle.pixelTop;
	this.m_finalW =3DsWidth =3DrStyle.pixelWidth;
	this.m_finalH =3DsHeight =3DrStyle.pixelHeight;
	clientW=3DSlideObj.style.pixelWidth-offsetL;
	clientH=3DSlideObj.style.pixelHeight-offsetT;
 	if(dir < 100) {
		switch(dir) {
			case 0: case 12: sLeft=3D-(sWidth+offsetL); break;
			case 1: case 13: sTop=3D-(sHeight+offsetT);	break;
			case 2: case 14: sLeft=3DclientW; break;
			case 3: case 15: sTop=3DclientH; break;
			case 4:=20
				sLeft=3D-(sWidth+offsetL);=20
				sTop=3D-(sHeight+offsetT);=20
				break;
			case 5:=20
				sLeft=3DclientW;=20
				sTop=3D-(sHeight+offsetT);=20
				break;
			case 6:=20
				sLeft=3D-(sWidth+offsetL);=20
				sTop=3DclientH;=20
				break;
			case 7:=20
				sLeft=3DclientW;=20
				sTop=3DclientH;=20
				break;
			case 8: sLeft-=3DsWidth; break;
			case 9: sTop+=3DsHeight; break;
			case 10: sLeft+=3DsWidth; break;
			case 11: sTop-=3DsHeight; break;
			case 16:
				sLeft+=3DsWidth/2;
				sTop+=3DsHeight/2;
				sWidth=3D0;
				sHeight=3D0;
				break;
			case 17:
				sLeft+=3DsWidth/6;
				sTop+=3DsHeight/6;
				sWidth=3DsWidth*2/3;
				sHeight=3DsHeight*2/3;
				break;
			case 18:
				sLeft-=3D(3*sWidth)/2;
				sTop-=3D(3*sHeight)/2;
				sWidth=3DsWidth*4;
				sHeight=3DsHeight*4;
				break;
			case 19:
				sLeft-=3DsWidth/6;
				sTop-=3DsHeight/6;
				sWidth=3DsWidth*4/3;
				sHeight=3DsHeight*4/3;
				break;
			case 20:
				sLeft=3DclientW/2;
				sTop=3DclientH/2;
				sWidth=3D0;
				sHeight=3D0;
				break;
			case 21:
				sLeft=3D 0;=20
				sTop=3DclientH;=20
				sWidth=3DclientW;=20
				sHeight=3DclientH;
				break;
			case 22:
				sLeft+=3DsWidth/2;
				sWidth=3D0;
				break;
			case 23: sWidth=3D0; break;
			case 24: sHeight=3D0; break;
			case 25:
				sLeft+=3DsWidth;
				sWidth=3D0;
				break;
			case 26:
				sTop+=3DsHeight;
				sHeight=3D0;
				break;
			case 27:
				sLeft+=3DsWidth/2;
				sWidth=3D0;
				break;
			case 28:
				sLeft=3D0;
				sTop=3DclientH;
				sWidth=3D0;
				sHeight=3D0;
				break;
		}
	}
	if(0 =3D=3D sWidth)=20
		sWidth++;
	rStyle.pixelLeft=3DsLeft;
	rStyle.pixelTop=3DsTop;
	rStyle.pixelWidth=3DsWidth;
	rStyle.pixelHeight=3DsHeight;
}
function A_DoInplace(){
	if(this.m_animObj.filters.revealtrans){
		this.m_animObj.filters.revealtrans.Apply();
		this.m_animObj.style.visibility =3D"visible";
		this.m_animObj.filters.revealtrans.Play();
	}
}
function A_DoMove(){
	rStyle =3D this.m_animObj.style;
	rStyle.pixelLeft +=3D(this.m_finalL - rStyle.pixelLeft)/this.m_steps;
	rStyle.pixelTop +=3D(this.m_finalT - rStyle.pixelTop)/this.m_steps;
	rStyle.pixelWidth +=3D(this.m_finalW - rStyle.pixelWidth)/this.m_steps;
	rStyle.pixelHeight +=3D(this.m_finalH - =
rStyle.pixelHeight)/this.m_steps;
}=20
function A_DoSpiral(){
	ratio =3Dthis.m_steps / GetSteps(this.m_build);
	angle =3D2*ratio*3.14;
	cosa =3DMath.cos(angle);
	sina =3DMath.sin(angle);
	vx =3D(this.m_finalL + this.m_finalW / 2)*ratio;
	vy =3D(this.m_finalT + this.m_finalH / 2 - SlideObj.style.pixelHeight) =
* ratio;
	rStyle =3Dthis.m_animObj.style;
	rStyle.pixelLeft =3Dthis.m_finalL - vx * cosa - vy * sina;
	rStyle.pixelTop =3Dthis.m_finalT + vx * sina - vy * cosa;
	rStyle.pixelWidth =3Dthis.m_finalW * (1 - ratio);
	rStyle.pixelHeight =3Dthis.m_finalH * (1 - ratio);
}
function A_DoSwivel(){
	rStyle =3Dthis.m_animObj.style;
	angle =3Dthis.m_steps / GetSteps(this.m_build) * 5 * 3.14 / 2;
	difX =3DMath.abs(this.m_finalW * Math.cos(angle));
	rStyle.pixelLeft =3Dthis.m_finalL + (this.m_finalW - difX) / 2;
	if(0 =3D=3D difX) difX++;
	rStyle.pixelWidth =3DdifX;
}
function DocumentOnClick()
{
	if( IsNts() || parent.HideMenu() ) return
	_DocAction()
}
function _DocAction()
{
	if( g_animManager && g_animManager.m_isPlaying && g_curAnim )
		StopMedia( g_curAnim.m_video );

	if( ( g_showAnimation && !g_curAnim &&=20
		g_animManager && g_animManager.Next() ) )
		return;

	if( ( g_allowAdvOnClick && (window.name=3D=3D"PPTSld") && =
!parent.IsFramesMode() &&=20
		!g_curAnim ) || (!g_curAnim && event && event.keyCode=3D=3D32) )
		parent.GoToNextSld();
}


var g_supportsPPTHTML =3D SupportsPPTHTML(), g_scaleInFrame =3D true, =
gId=3D"", g_bgSound=3D"",
    g_scaleHyperlinks =3D false, g_allowAdvOnClick =3D true, =
g_showInBrowser =3D false;
var g_showAnimation =3D g_supportsPPTHTML && SupportsPPTAnimation() && ( =
(window.name=3D=3D"PPTSld" && !parent.IsFramesMode()) || g_showInBrowser =
);var g_hasTrans =3D false, g_autoTrans =3D false, g_transSecs =3D 0;
var g_isKiosk =3D 0;var g_animManager =3D null;

var ENDSHOW_MESG=3D"End of slide show, click to exit.", =
SCREEN_MODE=3D"Frames", gIsEndShow=3D0, NUM_VIS_SLDS=3D30, =
SCRIPT_HREF=3D"script.js", FULLSCR_HREF=3D"fullscreen.htm";
var gCurSld =3D gPrevSld =3D 1, g_offset =3D 0, gNtsOpen =3D gHasNts =3D =
gOtlTxtExp =3D gNarrationPaused =3D false, gOtlOpen =3D true
window.gPPTHTML=3DSupportsPPTHTML()

function UpdNtsPane(){ PPTNts.location.replace( MHTMLPrefix+GetHrefObj( =
gCurSld ).mNtsHref ) }
function UpdNavPane( sldIndex ){ if(gNavLoaded) PPTNav.UpdNav() }
function UpdOtNavPane(){ if(gOtlNavLoaded) PPTOtlNav.UpdOtlNav() }
function UpdOtlPane(){ if(gOtlLoaded) PPTOtl.UpdOtl() }
function SetHasNts( fVal )
{
	if( gHasNts !=3D fVal ) {
		gHasNts=3DfVal
		UpdNavPane()
	}
}
function ToggleOtlText()
{
	gOtlTxtExp=3D!gOtlTxtExp
	UpdOtlPane()
}
function ToggleOtlPane()
{
	frmset=3Ddocument.all("PPTHorizAdjust")
	frm=3Ddocument.all("PPTOtl")

	if( gOtlOpen )
		frmset.cols=3D"*,100%"
	else
		frmset.cols=3D"20%,80%"

	gOtlOpen=3D!gOtlOpen
	frm.noResize=3D!frm.noResize
	UpdOtNavPane()
}
function ToggleNtsPane()
{
	frmset=3Ddocument.all("PPTVertAdjust")
	frm=3Ddocument.all("PPTNts")

	if( gNtsOpen )
		frmset.rows=3D"100%,*"
	else
		frmset.rows=3D"80%,20%"

	gNtsOpen=3D!gNtsOpen
	UpdNtsPane()
}
function FullScreen(){ window.open( =
MHTMLPrefix+FULLSCR_HREF,null,"fullscreen=3Dyes" ) }
function ToggleVNarration()
{
	rObj=3DPPTSld.document.all("NSPlay")
	if( rObj ) {
		if( gNarrationPaused )
			rObj.Play()
		else
			rObj.Pause()

		gNarrationPaused=3D!gNarrationPaused
	}
}
function GetCurSldNum()
{  =20
	obj=3DGetHrefObj(gCurSld)
	if( obj.mOrigVis =3D=3D 1 )
		return obj.mSldIdx
	else  =20
		return gCurSld
}
function GetNumSlds()
{  =20
	if( GetHrefObj(gCurSld).mOrigVis =3D=3D 1 )
		return NUM_VIS_SLDS
	else
		return gDocTable.length
}
function GetSldNum( href )
{
	for(ii=3D0; ii<gDocTable.length; ii++) {
		if ( gDocTable[ii].mSldHref =3D=3D href )
			return ii+1
	}
	return 1
}
function GetHrefObj( sldIdx ){ return gDocTable[sldIdx-1] }
function IsFramesMode(){ return ( SCREEN_MODE =3D=3D "Frames" ) }
function IsFullScrMode(){ return ( SCREEN_MODE =3D=3D "FullScreen" ) }
function GoToNextSld()
{  =20
	ii=3DgCurSld + 1
	if( GetHrefObj( ii-1 ).mOrigVis =3D=3D 0 ) {
		if( ii<=3DgDocTable.length ) {
			obj=3DGetHrefObj(ii)
			obj.mVis=3D1
			GoToSld(obj.mSldHref)
			return
		}	=09
	}
	else {
		obj=3DGetHrefObj( ii )
		while ( obj && ( obj.mOrigVis =3D=3D 0 ) )
			obj=3DGetHrefObj(ii++)
		if( obj && obj.mOrigVis ) {
			GoToSld(obj.mSldHref)=09
			return
		}=09
	}
	if( !IsFramesMode() ) EndShow()
}
function GoToPrevSld()
{
	ii=3DgCurSld-1
	if( ii > 0 ) {     =20
		obj=3DGetHrefObj(ii)
		while ( ( obj.mVis =3D=3D 0 ) && ( ii>0 ) )
			obj=3DGetHrefObj(ii--)
		GoToSld(obj.mSldHref)
	}
}
function GoToFirst(){ GoToSld( GetHrefObj(1).mSldHref ) }
function GoToLast()
{
	ii=3DgDocTable.length
	if( ii !=3D gCurSld )
		GoToSld( GetHrefObj(ii).mSldHref )
}
function GoToSld( href )
{
	if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue
	GetHrefObj( GetSldNum(href) ).mVis=3D1
	PPTSld.location.href=3DMHTMLPrefix+href
}
function SldUpdated( id )
{
	if( id =3D=3D GetHrefObj(gCurSld).mSldHref ) return
	gPrevSld=3DgCurSld
	gCurSld=3DGetSldNum(id)
	if( IsFramesMode() ) {
		UpdNavPane(); UpdOtlPane(); UpdNtsPane()
	}
}

function PrevSldViewed(){ GoToSld( GetHrefObj(gPrevSld).mSldHref ) }
function HasPrevSld() { return ( gIsEndShow || ( gCurSld !=3D 1 && =
GetHrefObj( gCurSld-1 ).mVis =3D=3D 1 )||( GetCurSldNum() > 1 ) ) }
function HasNextSld() { return (GetCurSldNum() !=3D GetNumSlds()) }
function EndShow()
{
	if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue

	doc=3DPPTSld.document
	doc.open()
	doc.writeln('<html><head><script defer>function CloseWindow(){ if( =
parent.HideMenu() ) return; if( !parent.IsFramesMode() && event && =
(event.keyCode=3D=3D27 || event.keyCode=3D=3D32 || =
event.type=3D=3D"click" ) ) parent.window.close( self ); } function =
Unload() { parent.gIsEndShow=3D0; } function SetupEndShow() { =
parent.gIsEndShow=3D1; document.body.scroll=3D"no"; =
document.onkeypress=3DCloseWindow; document.onclick=3DCloseWindow; =
document.oncontextmenu=3Dparent._CM; }</script></head><body =
bgcolor=3Dblack onload=3DSetupEndShow() =
onunload=3DUnload()><center><p><font face=3DTahoma color=3Dwhite =
size=3D2><br><b>' + ENDSHOW_MESG + =
'</b></font></p></center></body></html>')
	doc.close()
}
function SetSldVisited(){ gDocTable[gCurSld-1].mVisited=3Dtrue }
function IsSldVisited(){ return gDocTable[gCurSld-1].mVisited }
function hrefList( sldHref, visible, sldIdx )
{
	this.mSldHref=3D this.mNtsHref =3D sldHref
	this.mSldIdx =3D sldIdx
	this.mOrigVis=3D this.mVis =3D visible
	this.mVisited=3D false
}
var gDocTable =3D new Array(
   new hrefList("slide0001.htm", 1, 1),
   new hrefList("slide0027.htm", 1, 2),
   new hrefList("slide0010.htm", 1, 3),
   new hrefList("slide0023.htm", 1, 4),
   new hrefList("slide0025.htm", 1, 5),
   new hrefList("slide0026.htm", 1, 6),
   new hrefList("slide0022.htm", 1, 7),
   new hrefList("slide0011.htm", 1, 8),
   new hrefList("slide0028.htm", 1, 9),
   new hrefList("slide0029.htm", 1, 10),
   new hrefList("slide0032.htm", 1, 11),
   new hrefList("slide0031.htm", 1, 12),
   new hrefList("slide0030.htm", 1, 13),
   new hrefList("slide0033.htm", 1, 14),
   new hrefList("slide0034.htm", 1, 15),
   new hrefList("slide0035.htm", 1, 16),
   new hrefList("slide0003.htm", 1, 17),
   new hrefList("slide0006.htm", 1, 18),
   new hrefList("slide0004.htm", 1, 19),
   new hrefList("slide0005.htm", 1, 20),
   new hrefList("slide0008.htm", 1, 21),
   new hrefList("slide0043.htm", 1, 22),
   new hrefList("slide0044.htm", 1, 23),
   new hrefList("slide0041.htm", 1, 24),
   new hrefList("slide0036.htm", 1, 25),
   new hrefList("slide0037.htm", 1, 26),
   new hrefList("slide0042.htm", 1, 27),
   new hrefList("slide0038.htm", 1, 28),
   new hrefList("slide0039.htm", 1, 29),
   new hrefList("slide0040.htm", 1, 30)
);

function ImgBtn( oId,bId,w,action )
{
	var t=3Dthis
	t.Perform    =3D _IBP
	t.SetActive  =3D _IBSetA
	t.SetInactive=3D _IBSetI
	t.SetPressed =3D _IBSetP
	t.SetDisabled=3D _IBSetD
	t.Enabled    =3D _IBSetE
	t.ChangeIcon =3D null
	t.UserAction =3D action
	t.ChgState   =3D _IBUI
	t.mObjId   =3D oId
	t.mBorderId=3D bId
	t.mWidth   =3D w
	t.mIsOn    =3D t.mCurState =3D 0
}
function _IBSetA()
{
	if( this.mIsOn ) {
		obj=3Dthis.ChgState( gHiliteClr,gShadowClr,2 )
		obj.style.posTop=3D0
	}
}
function _IBSetI()
{
	if( this.mIsOn ) {
		obj=3Dthis.ChgState( gFaceClr,gFaceClr,1 )
		obj.style.posTop=3D0=20
	}
}
function _IBSetP()
{
	if( this.mIsOn ) {
		obj=3Dthis.ChgState( gShadowClr,gHiliteClr,2 )
		obj.style.posLeft+=3D1; obj.style.posTop+=3D1
	}
}
function _IBSetD()
{ =20
	obj=3Dthis.ChgState( gFaceClr,gFaceClr,0 )
	obj.style.posTop=3D0=20
}
function _IBSetE( state )
{
	var t=3Dthis
	GetObj( t.mBorderId ).style.visibility=3D"visible"
	if( state !=3D t.mIsOn ) {
		t.mIsOn=3Dstate
		if( state )
			t.SetInactive()
		else
			t.SetDisabled()
	}
}
function _IBP()
{
	var t=3Dthis
	if( t.mIsOn ) {
		if( t.UserAction !=3D null )
			t.UserAction()
		if( t.ChangeIcon ) {
			obj=3DGetObj(t.mObjId)
			if( t.ChangeIcon() )
				obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-4)*t.mWidth
			else
				obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-0)*t.mWidth
		}
		t.SetActive()
	} =20
}
function _IBUI( clr1,clr2,nextState )
{
	var t=3Dthis
	SetBorder( GetObj( t.mBorderId ),clr1,clr2 )
	obj=3DGetObj( t.mObjId )
	=
obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-nextState)*t.mWidth-ob=
j.style.posTop
	t.mCurState=3DnextState
	return obj
}
function TxtBtn( oId,oeId,action,chkState )
{
	var t=3Dthis
	t.Perform    =3D _TBP
	t.SetActive  =3D _TBSetA
	t.SetInactive=3D _TBSetI
	t.SetPressed =3D _TBSetP
	t.SetDisabled=3D _TBSetD
	t.SetEnabled =3D _TBSetE
	t.GetState   =3D chkState
	t.UserAction =3D action
	t.ChgState   =3D _TBUI
	t.mObjId      =3D oId
	t.m_elementsId=3D oeId
	t.mIsOn       =3D 1
}
function _TBSetA()
{
	var t=3Dthis
	if( t.mIsOn && !t.GetState() )
		t.ChgState( gHiliteClr,gShadowClr,0,0 )
}
function _TBSetI()
{
	var t=3Dthis
	if( t.mIsOn && !t.GetState() )
		t.ChgState( gFaceClr,gFaceClr,0,0 )
}
function _TBSetP()
{
	if( this.mIsOn )
		this.ChgState( gShadowClr,gHiliteClr,1,1 )
}
function _TBSetD()
{  =20
	this.ChgState( gFaceClr,gFaceClr,0,0 )
	this.mIsOn =3D 0
}
function _TBSetE()
{
	var t=3Dthis
	if( !t.GetState() )
		t.ChgState( gFaceClr,gFaceClr,0,0 )
	else
		t.ChgState( gShadowClr,gHiliteClr,1,1 )
	t.mIsOn =3D 1
}
function _TBP()
{
	var t=3Dthis
	if( t.mIsOn ) {=20
		if( t.UserAction !=3D null )
			t.UserAction()
		if( t.GetState() )
			t.SetPressed()
		else
			t.SetActive()
	} =20
}
function _TBUI( clr1,clr2,lOffset,tOffset )
{
	SetBorder( GetObj( this.mObjId ),clr1,clr2 )
	Offset( GetObj( this.m_elementsId ),lOffset,tOffset )
}
function GetObj( objId ){ return document.all.item( objId ) }
function Offset( obj, top, left ){ obj.style.top=3Dtop; =
obj.style.left=3Dleft }
function SetBorder( obj, upperLeft, lowerRight )
{
	s=3Dobj.style;
	s.borderStyle      =3D "solid"
	s.borderWidth      =3D 1=20
	s.borderLeftColor  =3D s.borderTopColor =3D upperLeft
	s.borderBottomColor=3D s.borderRightColor =3D lowerRight
}
function GetBtnObj(){ return gBtnArr[window.event.srcElement.id] }
function BtnOnOver(){ b=3DGetBtnObj(); if( b !=3D null ) b.SetActive() }
function BtnOnDown(){ b=3DGetBtnObj(); if( b !=3D null ) b.SetPressed() =
}
function BtnOnOut(){ b=3DGetBtnObj(); if( b !=3D null ) b.SetInactive() =
}
function BtnOnUp()
{
	b=3DGetBtnObj()
	if( b !=3D null )
		b.Perform()
	else
		Upd()
}
function GetNtsState(){ return parent.gNtsOpen }
function GetOtlState(){ return parent.gOtlOpen }
function GetOtlTxtState(){ return parent.gOtlTxtExp }
function NtsBtnSetFlag( fVal )
{
	s=3Ddocument.all.item( this.m_flagId ).style
	s.display=3D"none"
	if( fVal )
		s.display=3D""
	else
		s.display=3D"none"
}

var =
gHiliteClr=3D"THREEDHIGHLIGHT",gShadowClr=3D"THREEDSHADOW",gFaceClr=3D"TH=
REEDFACE"
var gBtnArr =3D new Array()
gBtnArr["nb_otl"] =3D new TxtBtn( =
"nb_otl","nb_otlElem",parent.ToggleOtlPane,GetOtlState )
gBtnArr["nb_nts"] =3D new TxtBtn( =
"nb_nts","nb_ntsElem",parent.ToggleNtsPane,GetNtsState )
gBtnArr["nb_prev"]=3D new ImgBtn( =
"nb_prev","nb_prevBorder",30,parent.GoToPrevSld )
gBtnArr["nb_next"]=3D new ImgBtn( =
"nb_next","nb_nextBorder",30,parent.GoToNextSld )
gBtnArr["nb_sldshw"]=3D new ImgBtn( =
"nb_sldshw","nb_sldshwBorder",18,parent.FullScreen )
gBtnArr["nb_voice"]  =3D new ImgBtn( =
"nb_voice","nb_voiceBorder",18,parent.ToggleVNarration )
gBtnArr["nb_otlTxt"]=3D new ImgBtn( =
"nb_otlTxt","nb_otlTxtBorder",23,parent.ToggleOtlText )
gBtnArr["nb_nts"].m_flagId=3D "notes_flag"
gBtnArr["nb_nts"].SetFlag =3D NtsBtnSetFlag
gBtnArr["nb_otlTxt"].ChangeIcon=3D GetOtlTxtState
var sNext=3D"Next",sPrev=3D"Previous",sEnd=3D"End Show",sFont=3D"Arial"
function ShowMenu()
{
	BuildMenu();
	var =
doc=3DPPTSld.document.body,x=3DPPTSld.event.clientX+doc.scrollLeft,y=3DPP=
TSld.event.clientY+doc.scrollTop

	m =3D PPTSld.document.all.item("ctxtmenu")
	m.style.pixelLeft=3Dx
	if( (x+m.scrollWidth > doc.clientWidth)&&(x-m.scrollWidth > 0) )
		m.style.pixelLeft=3Dx-m.scrollWidth

	m.style.pixelTop=3Dy
	if( (y+m.scrollHeight > doc.clientHeight)&&(y-m.scrollHeight > 0) )
		m.style.pixelTop=3Dy-m.scrollHeight

	m.style.display=3D""
}
function _CM()
{
	if( !parent.IsFullScrMode() ) return;
	if(!PPTSld.event.ctrlKey) {
		ShowMenu()
		return false
	} else
		HideMenu()
}
function BuildMenu()
{
	if( PPTSld.document.all.item("ctxtmenu") ) return

	var mObj=3DCreateItem( PPTSld.document.body )
	mObj.id=3D"ctxtmenu"
	var s=3DmObj.style
	s.position=3D"absolute"
	s.cursor=3D"default"
	s.width=3D"100px"
	SetCMBorder(mObj,"menu","black")

	var iObj=3DCreateItem( mObj )
	SetCMBorder( iObj, "threedhighlight","threedshadow" )
	iObj.style.padding=3D2
	CreateMenuItem( iObj,sNext,M_GoNextSld,M_True )
	CreateMenuItem( iObj,sPrev,M_GoPrevSld,M_HasPrevSld )
	var sObj=3DCreateItem( iObj )
	SetCMBorder(sObj,"menu","menu")
	var s=3DsObj.style
	s.borderTopColor=3D"threedshadow"
	s.borderBottomColor=3D"threedhighlight"
	s.height=3D1
	s.fontSize=3D"0px"
	CreateMenuItem( iObj,sEnd,M_End,M_True )
}
function Highlight() { ChangeClr("activecaption","threedhighlight") }
function Deselect() { ChangeClr("threedface","menutext") }
function Perform()
{
	e=3DPPTSld.event.srcElement
	if( e.type=3D=3D"menuitem" && e.IsActive() )
		e.Action()
	else
		PPTSld.event.cancelBubble=3Dtrue
}
function ChangeClr( bg,clr )
{
	e=3DPPTSld.event.srcElement
	if( e.type=3D=3D"menuitem" && e.IsActive() ) {
		e.style.backgroundColor=3Dbg
		e.style.color=3Dclr
	}
}

function M_HasPrevSld() { return( parent.HasPrevSld() ) }
function M_GoNextSld() { if( gIsEndShow ) M_End(); else GoToNextSld() }
function M_GoPrevSld() { if( gIsEndShow ) { history.back(); =
PPTSld.event.cancelBubble=3Dtrue; } else GoToPrevSld() }
function M_True() { return true }
function M_End() { window.close( self ) }
function CreateMenuItem( node,text,action,eval )
{
	var e=3DCreateItem( node )
	e.type=3D"menuitem"
	e.Action=3Daction
	e.IsActive=3Deval
	e.innerHTML=3Dtext

	if( !e.IsActive() )
		e.style.color=3D"threedshadow"
	e.onclick=3DPerform
	e.onmouseover=3DHighlight
	e.onmouseout=3DDeselect
	s=3De.style;
	s.fontFamily=3DsFont
	s.fontSize=3D"8pt"
	s.paddingLeft=3D2
}
function CreateItem( node )
{
	var elem=3DPPTSld.document.createElement("DIV")
	node.insertBefore( elem )
	return elem
}
function SetCMBorder( o,ltClr,rbClr )
{
	var s=3Do.style
	s.backgroundColor=3D"menu"
	s.borderStyle=3D"solid"
	s.borderWidth=3D1
	s.borderColor=3DltClr+" "+rbClr+" "+rbClr+" "+ltClr
}
------=_NextPart_000_001C_01C87611.59ACFD50
Content-Type: multipart/alternative;
	boundary="----=_NextPart_001_0021_01C87611.59AF6E50"


------=_NextPart_001_0021_01C87611.59AF6E50
Content-Type: text/html;
	charset="iso-8859-1"
Content-Transfer-Encoding: quoted-printable
Content-Location: mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol on the Brain.mht

<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Frameset//EN">
<HTML><HEAD><TITLE>Actions of Alcohol on the Brain</TITLE>
<META http-equiv=3DContent-Type content=3D"text/html; =
charset=3Dwindows-1252">
<META content=3DPowerPoint.Slide name=3DProgId>
<META content=3D"MSHTML 6.00.6000.16608" name=3DGENERATOR><LINK =
id=3DMain-File=20
href=3D"/alcohol/bd295/metabbrain2001/Metabbrain2001.htm" =
rel=3DMain-File><LINK=20
href=3D"preview.wmf" rel=3DPreview><![if !ppt]>
<SCRIPT language=3DJavaScript>=0A=
<!--=0A=
=0A=
function SymError()=0A=
{=0A=
  return true;=0A=
}=0A=
=0A=
window.onerror =3D SymError;=0A=
=0A=
var SymRealWinOpen =3D window.open;=0A=
=0A=
function SymWinOpen(url, name, attributes)=0A=
{=0A=
  return (new Object());=0A=
}=0A=
=0A=
window.open =3D SymWinOpen;=0A=
=0A=
//-->=0A=
</SCRIPT>

<SCRIPT=20
src=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001=
_files/script.js"></SCRIPT>

<SCRIPT>
<!--
var gNavLoaded =3D gOtlNavLoaded =3D gOtlLoaded =3D false;
function Load()
{
	str=3Ddocument.location.hash,idx=3Dstr.indexOf('#')
	if(idx>=3D0) str=3Dstr.substr(1);
	if(str) PPTSld.location.replace(str);
}
//-->
</SCRIPT>
<![endif]></HEAD><FRAMESET rows=3D*,25 frameBorder=3D0 =
onload=3DLoad()><FRAMESET=20
id=3DPPTHorizAdjust frameSpacing=3D2 onload=3DLoad() =
cols=3D20%,80%><FRAME name=3DPPTOtl=20
src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/outline.htm"><FRAMESET=20
id=3DPPTVertAdjust frameSpacing=3D2 rows=3D100%,* frameBorder=3D1 =
onload=3DLoad()><FRAME=20
name=3DPPTSld=20
src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/slide0001.htm"><FRAME=20
name=3DPPTNts=20
src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/slide0001.htm"></FRAMESET></FRAMESET><FRAMESET=20
frameSpacing=3D2 frameBorder=3D0 onload=3DLoad() cols=3D20%,80%><FRAME =
name=3DPPTOtlNav=20
src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/outline.htm"=20
noResize scrolling=3Dno><FRAME name=3DPPTNav=20
src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/outline.htm"=20
noResize scrolling=3Dno></FRAMESET></FRAMESET></HTML>

------=_NextPart_001_0021_01C87611.59AF6E50
Content-Type: text/html;
	charset="iso-8859-1"
Content-Transfer-Encoding: quoted-printable
Content-Location: mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol on the Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001_files/outline.htm

<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN">
<HTML><HEAD>
<META http-equiv=3DContent-Type content=3D"text/html; =
charset=3Dwindows-1252">
<META content=3DPowerPoint.Slide name=3DProgId>
<META content=3D"MSHTML 6.00.6000.16608" name=3DGENERATOR><LINK =
id=3DMain-File=20
href=3D"/alcohol/bd295/metabbrain2001/Metabbrain2001.htm" =
rel=3DMain-File><LINK=20
href=3D"preview.wmf" rel=3DPreview>
<META content=3DNoIndex name=3DRobots>
<SCRIPT language=3DJavaScript>=0A=
<!--=0A=
=0A=
function SymError()=0A=
{=0A=
  return true;=0A=
}=0A=
=0A=
window.onerror =3D SymError;=0A=
=0A=
var SymRealWinOpen =3D window.open;=0A=
=0A=
function SymWinOpen(url, name, attributes)=0A=
{=0A=
  return (new Object());=0A=
}=0A=
=0A=
window.open =3D SymWinOpen;=0A=
=0A=
//-->=0A=
</SCRIPT>

<SCRIPT=20
src=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001=
_files/script.js"></SCRIPT>

<SCRIPT><!--

if( !(IsWin("PPTOtl")||IsWin("PPTNav")||IsWin("PPTOtlNav")) )
{
	obj =3D document.all.item("Main-File")
	parent.location.href=3Dobj.href
}

var =
gOtlHiliteClr=3D"#FFFFFF",gOtlNormalClr=3D"#000000",gOtlActiveClr=3D"#FFF=
F00",gSelected=3D"",gTxtState=3Dfalse,gChildEntryTable=3Dnew Array()

function Load()
{
	if( IsWin("PPTOtl" ) ){ LoadOtl(); parent.gOtlLoaded=3Dtrue; return }
	if( IsWin("PPTNav" ) ){ LoadNav("NavObj",UpdNav); =
parent.gNavLoaded=3Dtrue; return }
	if( IsWin("PPTOtlNav" ) ){ LoadNav("OtlNavObj",UpdOtlNav); =
parent.gOtlNavLoaded=3Dtrue; return }
}
function Upd(){ if( IsWin("PPTNav") ) LoadNav("NavObj",UpdNav) }
function LoadNav( oId,UpdFunc )
{
	document.ondragstart=3DCancelDrag
	document.onselectstart=3DCancelDrag
	document.body.style.margin=3D2
	UpdFunc()
	obj=3Ddocument.all.item(oId)
	obj.style.display=3D"block"
	obj.style.visibility=3D"visible"
	document.bgColor=3D"threedface"
}
function LoadOtl()
{
	document.ondragstart=3DCancelDrag
	document.onselectstart=3DCancelDrag
	OtlObj.style.display=3D"block"
	OtlObj.style.visibility=3D"visible"
	if( gOtlActiveClr =3D=3D "" ) gOtlActiveClr=3Ddocument.linkColor
	if( gOtlHiliteClr =3D=3D "" ) gOtlHiliteClr=3Ddocument.fgColor
	if( gOtlNormalClr =3D=3D "" )
		gOtlNormalClr=3Ddocument.bgColor
	else
		document.bgColor=3DgOtlNormalClr =20

	InitArray()

	if( ObjExists( parent.gCurSld ) ) {
		ChangeState( parent.gCurSld,gOtlNormalClr,gOtlHiliteClr )
		gSelected=3Dparent.gCurSld
	}
	else gSelected =3D -1

	UpdOtl()
}
function UpdOtl(){ UpdIdx(parent.gCurSld) }
function UpdIdx( idx )
{
	if( gSelected !=3D idx ) {
		if( gSelected > 0 )
			ChangeState( gSelected,gOtlHiliteClr,gOtlNormalClr )

		if( ObjExists( idx ) ) {
			gSelected =3D idx
			ChangeState( gSelected,gOtlNormalClr,gOtlHiliteClr )
		}
		else gSelected =3D -1
	}

	if( gTxtState !=3D parent.gOtlTxtExp ) {
		state =3D "block"
		if( !parent.gOtlTxtExp )
			state=3D"none"

		for(ii=3D0; ii<gChildEntryTable.length; ii++) {
			obj=3DgChildEntryTable[ii];
			if( obj.id =3D=3D null ) continue;

			if( obj.id.indexOf("PPTC") >=3D 0 )
				obj.style.display=3Dstate;
		}=20
		gTxtState=3Dparent.gOtlTxtExp
		if( ObjExists( gSelected ) )
			ChangeState( gSelected,gOtlNormalClr,gOtlHiliteClr )
	}
}
function InitArray()
{
	count=3D0
	for(ii=3D0; ii<document.all.tags("DIV").length; ii++) {
		obj=3Ddocument.all.tags("DIV").item(ii)
		if( obj.id =3D=3D null ) continue

		if( obj.id.indexOf("PPTC") >=3D 0 ) {  =20
			gChildEntryTable[count++]=3Dobj
			obj.children.tags("TABLE").item(0).style.borderColor=3DgOtlNormalClr
		}
	}
}
function ChangeState( idx,fgColor,bgColor )
{
	obj=3Ddocument.all.item("PPTL"+idx)
	obj.style.color=3DfgColor

	obj=3Ddocument.all.item("PPTP"+idx)
	obj.style.backgroundColor=3DbgColor

	obj=3Ddocument.all.item("PPTB"+idx)
	if( obj )
		obj.style.borderLeftColor=3Dobj.style.borderBottomColor=3DbgColor
}
function ChgClr( o,clr ){ if( o.id !=3D "PPTL"+gSelected ) =
o.style.color=3Dclr }
function Over( obj ){ ChgClr(obj,gOtlActiveClr) }
function Out( obj ){ ChgClr(obj,gOtlHiliteClr) }
function ObjExists( ii ) { obj=3Ddocument.all("PPTP"+ii ); return( obj ) =
}
function GoToSld( href ){ UpdIdx(parent.GetSldNum(href)); =
parent.GoToSld( href ) }
function CancelDrag(){ =
window.event.cancelBubble=3Dtrue;window.event.returnValue=3Dfalse}

function UpdNav()
{
	txt =3D "<center>";
	if( parent.GetHrefObj( parent.gCurSld ).mOrigVis =3D=3D 1 )
		txt +=3D "Slide " + parent.GetCurSldNum() + " of " + =
parent.GetNumSlds()
	else
		txt +=3D "Hidden Slide"
	txt +=3D "</center>";
	nav_text.innerHTML =3D txt;

	if( !parent.HasPrevSld() )
		gBtnArr["nb_prev"].Enabled(0)
	else
		gBtnArr["nb_prev"].Enabled(1)

	if( !parent.HasNextSld() )
		gBtnArr["nb_next"].Enabled(0)
	else
		gBtnArr["nb_next"].Enabled(1)
	gBtnArr["nb_nts"].SetEnabled()
	gBtnArr["nb_nts"].SetFlag( parent.gHasNts )

	gBtnArr["nb_sldshw"].Enabled(1)
	gBtnArr["nb_voice"].Enabled(1)
}

function UpdOtlNav()
{
	gBtnArr["nb_otl"].SetEnabled();

	if( parent.gOtlOpen )
		gBtnArr["nb_otlTxt"].Enabled( true );
	else
		document.all.item("nb_otlTxtBorder").style.visibility =3D "hidden";
}



//-->
</SCRIPT>

<STYLE>.PTxt {
	MARGIN-TOP: 5px; PADDING-LEFT: 5px; FONT-WEIGHT: bold; WIDTH: 100%; =
POSITION: relative
}
.CTxt {
	PADDING-LEFT: 10px; WIDTH: 100%; POSITION: relative
}
.CBorder {
	BORDER-RIGHT: black 1px solid; BORDER-TOP: black 1px solid; =
PADDING-BOTTOM: 5px; BORDER-LEFT: black 1px solid; WIDTH: 100%; =
BORDER-BOTTOM: black 1px solid; POSITION: relative
}
A {
	COLOR: white; TEXT-DECORATION: none
}
.button {
	BORDER-RIGHT: buttonface 1px solid; BORDER-TOP: buttonface 1px solid; =
BORDER-LEFT: buttonface 1px solid; WIDTH: 32px; BORDER-BOTTOM: =
buttonface 1px solid; POSITION: absolute; HEIGHT: 20px
}
</STYLE>
</HEAD>
<BODY onload=3DLoad() stats=3D"1"><!-- Start of DeepMetrix (.NET) =
StatScript -->
<SCRIPT language=3Djavascript>

var DMNETdomain =3D "";
var DMNETpage =3D window.location;
var DMNETversion =3D "86";
var DMNETsendTo =3D "//campus.hws.edu/dm.gif?";
var DMNETsession;

function dmneterr(){return true;}

window.onerror=3Ddmneterr;
var s =3D new Date();

if (navigator.userAgent.indexOf('Mac') >=3D 0 && s.getTimezoneOffset() =
>=3D 720)
  s.setTime (s.getTime() - 1440*60*1000);

var dmnetURL =3D location.protocol + =
DMNETsendTo+"v=3D"+DMNETversion+"&vst=3D1";
var dmnetCookieString =3D document.cookie.toString();

if(dmnetCookieString.indexOf("_dmnid") =3D=3D -1)
  {
    DMNETsession =3D parseInt( Math.random()*1000000 ) + "_" + =
s.getTime();
    var domStr =3D "";
    if(DMNETdomain !=3D "")
    {
      domStr =3D "domain=3D"+ DMNETdomain +";";
    }
    document.cookie =3D "_dmnid=3D" + DMNETsession + ";expires=3DMon, =
31-Dec-2008 00:00:00 GMT;"+domStr+"path=3D/;";
  }
dmnetCookieString =3D document.cookie.toString();
if(dmnetCookieString.indexOf('_dmnid') =3D=3D -1)
  {
    DMNETsession =3D "";
  }
else
  {
    if(dmnetCookieString.indexOf(';') =3D=3D -1)
      dmnetCookieString =3D dmnetCookieString.replace(/_dm/g, ';_dm');

    var start =3D dmnetCookieString.indexOf("_dmnid=3D") + 7;
    var end =3D dmnetCookieString.indexOf(";",start);

    if (end =3D=3D -1)
      end =3D dmnetCookieString.length;
    DMNETsession =3D unescape(dmnetCookieString.substring(start,end));
  }
dmnetURL +=3D "&id=3D"+DMNETsession+"&url=3D"+escape(DMNETpage) + =
"&ref=3D"+escape(document.referrer)+"&lng=3D" + ((!document.all ||  =
navigator.userAgent.match('Opera')) ? navigator.language : =
navigator.userLanguage) + "&tz=3D" + (Math.round(new Date('dec 1, =
2002').getTimezoneOffset()/60)*-1);
if(screen)
  dmnetURL +=3D "&scr=3D" + escape( screen.width + "x" + screen.height + =
" " + screen.colorDepth + "bpp" );

dmnetURL +=3D "&rnd=3D" + new Date().getTime();

if(document.layers)
{
  document.write("<la"+"yer name=3D\"DMStats\" visibility=3Dhide><img =
src=3D\""+dmnetURL+"\" height=3D1 width=3D1></la"+"yer>");
}
else
{
  document.write("<di"+"v id=3D\"DMStats\" =
STYLE=3D\"position:absolute;visibility:hidden;\"><img =
src=3D\""+dmnetURL+"\" height=3D1 width=3D1></di"+"v>");
}

</SCRIPT>
<!-- End of DeepMetrix (.NET) StatScript -->
<DIV onmouseup=3DBtnOnUp() onkeypress=3D_KPH() onmousedown=3DBtnOnDown() =
id=3DNavObj=20
onmouseover=3DBtnOnOver() style=3D"DISPLAY: none; VISIBILITY: hidden"=20
onmouseout=3DBtnOnOut() onload=3D"Load()">
<TABLE style=3D"VISIBILITY: hidden; WIDTH: 70px; POSITION: absolute" =
cellSpacing=3D0=20
cellPadding=3D0 align=3Dleft>
  <TBODY>
  <TR>
    <TD noWrap>
      <DIV id=3Dnb_ntsElem=20
      style=3D"PADDING-RIGHT: 3px; PADDING-LEFT: 3px; FONT-SIZE: 9pt; =
PADDING-BOTTOM: 3px; COLOR: buttontext; PADDING-TOP: 3px; FONT-FAMILY: =
Arial; POSITION: relative"=20
      align=3Dcenter><IMG id=3Dnotes_flag style=3D"DISPLAY: none" =
src=3D""=20
      border=3D0><SPAN style=3D"mso-spacerun: yes">&nbsp; =
</SPAN>Notes</DIV>
      <DIV id=3Dnb_nts title=3D"Show/Hide Notes"=20
      style=3D"LEFT: 0%; WIDTH: 100%; POSITION: absolute; TOP: 0%; =
HEIGHT: 100%"></DIV></TD></TR></TBODY></TABLE>
<TABLE style=3D"POSITION: relative" cellSpacing=3D0 cellPadding=3D0 =
align=3Dright>
  <TBODY>
  <TR>
    <TD>
      <DIV id=3Dnb_sldshwBorder=20
      style=3D"LEFT: -20px; WIDTH: 20px; POSITION: absolute; HEIGHT: =
20px">
      <DIV style=3D"CLIP: rect(0px 18px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_sldshw title=3D"Full Screen Slide Show"=20
      style=3D"LEFT: -254px; POSITION: relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV></TD>
    <TD>
      <DIV id=3Dnb_voiceBorder=20
      style=3D"DISPLAY: none; LEFT: -40px; WIDTH: 20px; POSITION: =
absolute; HEIGHT: 20px">
      <DIV style=3D"CLIP: rect(0px 18px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_voice title=3D"Pause/Play Narration"=20
      style=3D"LEFT: -290px; POSITION: relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV></TD></TR></TBODY></TABLE>
<TABLE style=3D"POSITION: relative" cellSpacing=3D0 cellPadding=3D0 =
align=3Dcenter>
  <TBODY>
  <TR>
    <TD noWrap>
      <DIV class=3Dbutton id=3Dnb_prevBorder style=3D"LEFT: -30px">
      <DIV style=3D"CLIP: rect(0px 30px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_prev title=3D"Previous Slide" style=3D"LEFT: 0px; =
POSITION: relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV><SPAN=20
      id=3Dnav_text=20
      style=3D"FONT-SIZE: 9pt; WIDTH: 100px; COLOR: buttontext; =
FONT-FAMILY: Arial; POSITION: relative; TOP: 3px"></SPAN>
      <DIV class=3Dbutton id=3Dnb_nextBorder>
      <DIV style=3D"CLIP: rect(0px 30px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_next title=3D"Next Slide" style=3D"LEFT: -90px; POSITION: =
relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV></TD></TR></TBODY></TABLE></DIV>
<DIV onmouseup=3DBtnOnUp() onkeypress=3D_KPH() onmousedown=3DBtnOnDown() =
id=3DOtlNavObj=20
onmouseover=3DBtnOnOver() style=3D"DISPLAY: none; VISIBILITY: hidden"=20
onmouseout=3DBtnOnOut() onload=3D"Load()">
<TABLE style=3D"WIDTH: 70px; POSITION: relative" cellSpacing=3D0 =
cellPadding=3D0=20
align=3Dleft>
  <TBODY>
  <TR>
    <TD noWrap>
      <DIV id=3Dnb_otlElem=20
      style=3D"PADDING-RIGHT: 3px; PADDING-LEFT: 3px; FONT-SIZE: 9pt; =
PADDING-BOTTOM: 3px; COLOR: buttontext; PADDING-TOP: 3px; FONT-FAMILY: =
Arial; POSITION: relative"=20
      align=3Dcenter>Outline</DIV>
      <DIV id=3Dnb_otl title=3D"Show/Hide Outline"=20
      style=3D"LEFT: 0%; WIDTH: 100%; POSITION: absolute; TOP: 0%; =
HEIGHT: 100%"></DIV></TD></TR></TBODY></TABLE>
<TABLE style=3D"POSITION: relative" cellSpacing=3D0 cellPadding=3D0 =
align=3Dcenter>
  <TBODY>
  <TR>
    <TD>
      <DIV id=3Dnb_otlTxtBorder=20
      style=3D"BORDER-RIGHT: buttonface 1px solid; BORDER-TOP: =
buttonface 1px solid; LEFT: -18px; BORDER-LEFT: buttonface 1px solid; =
WIDTH: 24px; BORDER-BOTTOM: buttonface 1px solid; POSITION: absolute; =
HEIGHT: 20px">
      <DIV style=3D"CLIP: rect(0px 22px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_otlTxt title=3D"Expand/Collapse Outline"=20
      style=3D"LEFT: -157px; POSITION: relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV></TD></TR></TBODY></TABLE></DIV>
<DIV id=3DOtlObj style=3D"DISPLAY: none; VISIBILITY: hidden">
<TABLE style=3D"FONT-SIZE: 9pt; FONT-FAMILY: Arial" width=3D"100%">
  <TBODY>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP1><FONT size=3D2><A id=3DPPTL1 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0001.htm');">Behavioral =
Manifestations of=20
      Alcohol Ingestion</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC1 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB1 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 1 to 2 drinks (.01-.05 g/dL BAC) -- =
euphoria=20
            and perceived reduction in anxiety</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 3 to 5 drinks (.06-.10 g/dL BAC) -- =
judgement=20
            and motor coordination impaired,<SPAN=20
            style=3D"mso-spacerun: yes">&nbsp; </SPAN>sometimes =
increased=20
            aggression</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 10 to 13 drinks (.20-.25 g/dL BAC) --=20
            sedation</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With<SPAN style=3D"mso-spacerun: =
yes">&nbsp;=20
            </SPAN>0.30 g/dL BAC -- memory impairment and loss of=20
            consciousness</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With<SPAN style=3D"mso-spacerun: =
yes">&nbsp;=20
            </SPAN>0.40 to .50 g/dL BAC -- depressed respiration , coma, =

            death</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP2><FONT size=3D2><A id=3DPPTL2 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0027.htm');">What=20
      Factors Determine a Person=92s BAC?</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC2 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB2 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Number of Drinks Consumed</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Time</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Body Size and Build</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Sex</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Is Stomach Empty or Full?</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Past Drinking Experiences</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP3><FONT size=3D2><A id=3DPPTL3 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      =
href=3D"javascript:GoToSld('slide0010.htm');">Alcohol</A></FONT></DIV></T=
D></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP4><FONT size=3D2><A id=3DPPTL4 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      =
href=3D"javascript:GoToSld('slide0023.htm');">Absorption</A></FONT></DIV>=

      <DIV class=3DCTxt id=3DPPTC4 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB4 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Rate of absorption is dependent =

          on:</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>concentration gradient between gut and=20
          blood</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>surface area of contact</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>degree of vascularization</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Effect of Food on =
Absorption</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>food dilutes alcohol in the digestive=20
          system</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>fatty foods are slow to digest and slow to =
move=20
            from the stomach to the small=20
      intestine</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP5><FONT size=3D2><A id=3DPPTL5 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0025.htm');">Estimation of=20
      BAC</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP6><FONT size=3D2><A id=3DPPTL6 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0026.htm');">What if=20
      we were to continue for five drinks?</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP7><FONT size=3D2><A id=3DPPTL7 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0022.htm');">Slide=20
      7</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP8><FONT size=3D2><A id=3DPPTL8 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0011.htm');">Slide=20
      8</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP9><FONT size=3D2><A id=3DPPTL9 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0028.htm');">Metabolic=20
      Differences Between Men and Women</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC9 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB9 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Women are smaller than =
men</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Women have lower total body =
water content=20
            (49%) than men (58%) of comparable size</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Gastric ADH lower in =
women</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>virtually nonexistent in alcoholic=20
        women</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>declines in men over 50</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Fluctuations in gonadal hormone =
levels=20
            during the menstrual cycle may affect the rate of alcohol=20
            metabolism</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP10><FONT size=3D2><A id=3DPPTL10 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0029.htm');">Metabolic=20
      Differences Between Ethnic Groups</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC10 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB10 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Isoenzymes in Alcohol DH=20
        (ADH)</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Beta1 in Caucasian has Km 0.00023 =
g/dL</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Beta2 in Asian has Km 0.0043 =
g/dL</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Beta3 in 15% African Amer. has Km .165=20
          g/dL</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>50% Chinese and Japanese Asians =
have=20
            inactive mito. Aldehyde DH (ALDH) resulting in facial =
flushing,=20
            palpitations, dizziness, and=20
    nausea</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP11><FONT size=3D2><A id=3DPPTL11 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0032.htm');">Effect of=20
      Chronic Use</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC11 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB11 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Metabolic Tolerance</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>But=85.This is not the whole story=85.more =
to=20
            come</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP12><FONT size=3D2><A id=3DPPTL12 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0031.htm');">Alcohol=20
      on the Brain</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP13><FONT size=3D2><A id=3DPPTL13 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0030.htm');">Behavioral =
Manifestations of=20
      Alcohol Ingestion</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC13 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB13 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 1 to 2 drinks (.01-.05 g/dL BAC) -- =
euphoria=20
            and perceived reduction in anxiety</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 3 to 5 drinks (.06-.10 g/dL BAC) -- =
judgement=20
            and motor coordination impaired,<SPAN=20
            style=3D"mso-spacerun: yes">&nbsp; </SPAN>sometimes =
increased=20
            aggression</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 10 to 13 drinks (.20-.25 g/dL BAC) --=20
            sedation</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With<SPAN style=3D"mso-spacerun: =
yes">&nbsp;=20
            </SPAN>0.30 g/dL BAC -- memory impairment and loss of=20
            consciousness</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With<SPAN style=3D"mso-spacerun: =
yes">&nbsp;=20
            </SPAN>0.40 to .50 g/dL BAC -- depressed respiration , coma, =

            death</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP14><FONT size=3D2><A id=3DPPTL14 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0033.htm');">The=20
      Brain=92s Division of Labor</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP15><FONT size=3D2><A id=3DPPTL15 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      =
href=3D"javascript:GoToSld('slide0034.htm');">Neurons</A></FONT></DIV></T=
D></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP16><FONT size=3D2><A id=3DPPTL16 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      =
href=3D"javascript:GoToSld('slide0035.htm');">Synapse</A></FONT></DIV></T=
D></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP17><FONT size=3D2><A id=3DPPTL17 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0003.htm');">Alcohol=20
      Affects Neuro-transmitter Function in the Brain</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC17 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB17 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Potentiates GABA receptor =
function</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Inhibits Glutamate receptor =
function</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Increases Dopamine =
concentration</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Increases Seratonin =
release</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Stimulates Opiate Neuropeptide=20
        Release</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP18><FONT size=3D2><A id=3DPPTL18 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0006.htm');">Affect on=20
      Dopamine, Serotonin, and Endogenous Opiates (BAC ~ .01--.05=20
      g/dL)</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC18 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB18 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Dopamine stimulates pleasure =
centers and=20
            functions in positive reinforcement</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>alcohol increases Dopamine concentrations =
in=20
            nucleus acumbens and other reward centers</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Serotonin functions in mood, =
sleep and=20
            positive reinforcement</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2><SPAN=20
            style=3D"mso-spacerun: yes">&nbsp;</SPAN>alcoholics and =
thrill seekers=20
            have low serotonin levels and alcohol consumption ( and =
thrill=20
            activities) brings theses levels up to =
normal.</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Serotonergic drugs have reduced alcohol =
consumption=20
            by alcoholics.</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Endorphins and Enkephalins are =
natural=20
            neural peptides that bind to opiate receptors and produce =
euphoric=20
            effects.</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Endorphins and Enkephalins are released by =
the=20
            brain when exposed to alcohol</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Euphoria seems to stimulate further=20
          drinking</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP19><FONT size=3D2><A id=3DPPTL19 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0004.htm');">Affect on=20
      GABA function<BR>(BAC &gt;=3D.06 g/dL)</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC19 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB19 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>GABA is major inhibitory=20
            neurotransmitter</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Alcohol Potentiates GABA =
receptor=20
            function</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>GABA receptor is site of action =

          of</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2><SPAN=20
            style=3D"mso-spacerun: yes">&nbsp;</SPAN>sedative/anesthetic =

            barbiturate, pentobarbitol</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>sedative/anxiolytic =
benzodiazipines</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Major Site of Affects=20
        include:</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>medial septal nucleus -- controls =
=93arousal=20
            state=94</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Purkinje neurons in cerebellar cortex -- =
controls=20
            sensory and motor activity</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>RO 15-4513 overcomes motor=20
            impairment</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP20><FONT size=3D2><A id=3DPPTL20 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0005.htm');">Affect on=20
      Glutamate Function<BR><SPAN style=3D"mso-spacerun: =
yes">&nbsp;</SPAN>(BAC=20
      ~.02--.2 g/dL)</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC20 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB20 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Glutamate is major excitatory=20
            neurotransmitter</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Alcohol inhibits NMDA glutamate =
receptor=20
            function</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Impaired NMDA Glutamate =
Receptor Function=20
            Causes:</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>cognitive impairment and =
amnesia</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>inability to learn new =
information</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Alcohol parallels action of PCP =
or =93angel=20
            dust=94</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP21><FONT size=3D2><A id=3DPPTL21 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0008.htm');">Effect of=20
      Chronic Use</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC21 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB21 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Tolerance</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>changes in number and types of GABA=20
          receptors</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Increase in number of glutamate=20
        receptors</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Withdrawal</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>increased Anxiety within hours -- =
GABA</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>seizures -- Glutamate</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Dependence</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>changes in Dopamine and Seratonin function =
appear=20
            to be long =
lasting</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP22><FONT size=3D2><A id=3DPPTL22 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0043.htm');">Important=20
      Metabolic Interactions and Health =
Concerns</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP23><FONT size=3D2><A id=3DPPTL23 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0044.htm');">Slide=20
      23</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP24><FONT size=3D2><A id=3DPPTL24 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0041.htm');">Interaction with =
other=20
      Drugs</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC24 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB24 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Ethyl ester of =
Cocaine</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>potentiates cocaine =
=93high=94</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Aspirin and Cimetidine<SPAN=20
            style=3D"mso-spacerun: yes">&nbsp; </SPAN>Inhibits Gastric=20
          ADH</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Liver Drug Detoxification=20
          Impaired</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Depleted NAD impairs livers ability to =
clear other=20
            drugs</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP25><FONT size=3D2><A id=3DPPTL25 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0036.htm');">Metabolic=20
      Fates of Excess Ethanol and Acetaldehyde</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC25 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB25 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Ethyl esters of Fatty Acids and =

            Cholesterol</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>may cause heart damage, impair energy =
metabolism,=20
            disrupt cell membranes</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Protein Modification by=20
            Acetaldehyde</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>enzymes inactivated by imine =
adducts</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Ethanol can also be oxidized by =

            MEOS/Cytochrome P450</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>MEOS oxidation produced harmful free=20
          radicals</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP26><FONT size=3D2><A id=3DPPTL26 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0037.htm');">Other=20
      Metabolic Processes Affected by Alcohol =
Metabolism</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC26 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB26 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>High NADH/NAD =
ratio:</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Impaired Energy Metabolism</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Inhibits Lipid Degredation in =
Liver</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Stimulation of fat synthesis and increases =
in LDL=20
            and HDL levels</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Inhibition of oxidative steps in =
testosterone=20
            synthesis</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP27><FONT size=3D2><A id=3DPPTL27 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0042.htm');">Slide=20
      27</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP28><FONT size=3D2><A id=3DPPTL28 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0038.htm');">Alcohol-Induced =
Liver=20
      Damage</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC28 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB28 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Risk becomes signficant when =
alcohol=20
            consumption exceeds</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>6.2oz/day for men</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>1.55oz/day for women</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Caused by</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Free radical rx in fatty =
liver</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Cytokine stimulated differentiation of Ito =
cells=20
            into collagen myofibroblasts</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Increased levels of Acetaldehyde due to =
lower=20
            levels of Aldehyde=20
  dehydrogenase</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP29><FONT size=3D2><A id=3DPPTL29 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0039.htm');">Alcohol-Induced =
Immune System=20
      Impairment</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC29 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB29 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Suppresses proliferation of lymphocytes in =
blood,=20
            spleen, and thymus</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Reduced B cell antibody =
production</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Natural Killer (NK) cells have reduced=20
            activity</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP30><FONT size=3D2><A id=3DPPTL30 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0040.htm');">Alcohol-Induced =
Changes in=20
      the<BR>Cardiovascular System</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC30 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB30 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Reduced risk of CAD with =
&lt;=3D2=20
            drinks/day</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>increased HDL, inhibition of platelet=20
            activity</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>50% greater risk of =
hypertension with 3-4=20
            drinks/day</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Cardiomyopathy (weakened heart=20
            muscle)</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>impaired protein metabolism, free=20
        radicals</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Arrhythmias caused by alcohol =
effect on=20
            sinoatrial node</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Cerebral Vascular Disease=20
          (Stroke)</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>reduced platelet=20
      =
activity</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR></TBODY></TABLE>=
</DIV>
<DIV style=3D"DISPLAY: none"><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03.xml"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/preview.wmf"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master02.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/pres.xml"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound001.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound002.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound003.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound004.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound005.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound006.wav"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/slide0001.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03_background.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03_image001.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0027.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0010.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0023.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0025.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0025_image002.emz"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/oledata.mso"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0025_image003.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image004.emz"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image005.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image006.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image007.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image008.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image009.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022_image010.emz"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022_image011.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022_image012.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022_image013.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image014.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image015.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image016.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image017.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image018.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0028.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0029.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0032.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0032_image019.emz"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0032_image020.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0031.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0030.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image021.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image022.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image023.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image024.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image025.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image026.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image027.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0034.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0034_image028.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0034_image029.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0035.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0035_image030.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0035_image031.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0003.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0006.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0004.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0005.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0008.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0043.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image032.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image033.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image034.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image035.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image036.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0041.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0036.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0037.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0042.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0038.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0039.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0040.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master01.htm"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/master03_stylesheet.css"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/script.js"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/error.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/fullscreen.htm"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/frame.htm"></A><A=20
href=3D"about:blank"></A></DIV>
<SCRIPT language=3DJavaScript>=0A=
<!--=0A=
var SymRealOnLoad;=0A=
var SymRealOnUnload;=0A=
=0A=
function SymOnUnload()=0A=
{=0A=
  window.open =3D SymWinOpen;=0A=
  if(SymRealOnUnload !=3D null)=0A=
     SymRealOnUnload();=0A=
}=0A=
=0A=
function SymOnLoad()=0A=
{=0A=
  if(SymRealOnLoad !=3D null)=0A=
     SymRealOnLoad();=0A=
  window.open =3D SymRealWinOpen;=0A=
  SymRealOnUnload =3D window.onunload;=0A=
  window.onunload =3D SymOnUnload;=0A=
}=0A=
=0A=
SymRealOnLoad =3D window.onload;=0A=
window.onload =3D SymOnLoad;=0A=
=0A=
//-->=0A=
</SCRIPT>
</BODY></HTML>

------=_NextPart_001_0021_01C87611.59AF6E50--

------=_NextPart_000_001C_01C87611.59ACFD50
Content-Type: text/css;
	charset="iso-8859-1"
Content-Transfer-Encoding: quoted-printable
Content-Location: http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001_files/master03_stylesheet.css

BODY {
	WIDTH: 534px; HEIGHT: 400px
}
.T {
	FONT-SIZE: 209%; COLOR: #8cf4ea; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 3
}
.BB {
	FONT-SIZE: 75%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: bulletn
}
.B {
	FONT-SIZE: 152%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1; text-shadow: auto
}
.B1B {
	FONT-SIZE: 75%; COLOR: #618ffd; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 7; mso-special-format: bulletu
}
.B1 {
	FONT-SIZE: 133%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1; text-shadow: auto
}
.B2B {
	FONT-SIZE: 65%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: bulletF
}
.B2 {
	FONT-SIZE: 114%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1; text-shadow: auto
}
.B3B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
bullet=95
}
.B3 {
	FONT-SIZE: 95%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1; text-shadow: auto
}
.B4B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
bullet=96
}
.B4 {
	FONT-SIZE: 95%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1; text-shadow: auto
}
.N {
	FONT-SIZE: 57%; COLOR: black; FONT-FAMILY: Arial; TEXT-ALIGN: left; =
mso-color-index: 1
}
.N1 {
	FONT-SIZE: 57%; COLOR: black; FONT-FAMILY: Arial; TEXT-ALIGN: left; =
mso-color-index: 1
}
.N2 {
	FONT-SIZE: 57%; COLOR: black; FONT-FAMILY: Arial; TEXT-ALIGN: left; =
mso-color-index: 1
}
.N3 {
	FONT-SIZE: 57%; COLOR: black; FONT-FAMILY: Arial; TEXT-ALIGN: left; =
mso-color-index: 1
}
.N4 {
	FONT-SIZE: 57%; COLOR: black; FONT-FAMILY: Arial; TEXT-ALIGN: left; =
mso-color-index: 1
}
.O {
	FONT-SIZE: 114%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1
}
.O1 {
	FONT-SIZE: 114%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1
}
.CBB {
	FONT-SIZE: 75%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: nobulletn
}
.CB {
	text-shadow: auto
}
.CB1B {
	FONT-SIZE: 75%; COLOR: #618ffd; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 7; mso-special-format: nobulletu
}
.CB1 {
	text-shadow: auto
}
.CB2B {
	FONT-SIZE: 65%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: nobulletF
}
.CB2 {
	text-shadow: auto
}
.CB3B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
nobullet=95
}
.CB3 {
	text-shadow: auto
}
.CB4B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
nobullet=96
}
.CB4 {
	text-shadow: auto
}
.CT {
	FONT-SIZE: 209%; COLOR: #8cf4ea; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 3
}
.HBB {
	FONT-SIZE: 75%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: bulletn
}
.HB {
	text-shadow: auto
}
.HB1B {
	FONT-SIZE: 75%; COLOR: #618ffd; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 7; mso-special-format: bulletu
}
.HB1 {
	text-shadow: auto
}
.HB2B {
	FONT-SIZE: 65%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: bulletF
}
.HB2 {
	text-shadow: auto
}
.HB3B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
bullet=95
}
.HB3 {
	text-shadow: auto
}
.HB4B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
bullet=96
}
.HB4 {
	text-shadow: auto
}
.QBB {
	FONT-SIZE: 75%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: bulletn
}
.QB {
	text-shadow: auto
}
.QB1B {
	FONT-SIZE: 75%; COLOR: #618ffd; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 7; mso-special-format: bulletu
}
.QB1 {
	text-shadow: auto
}
.QB2B {
	FONT-SIZE: 65%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: bulletF
}
.QB2 {
	text-shadow: auto
}
.QB3B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
bullet=95
}
.QB3 {
	text-shadow: auto
}
.QB4B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
bullet=96
}
.QB4 {
	text-shadow: auto
}
.TblB {
	FONT-SIZE: 75%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: nobulletn
}
.Tbl {
	text-shadow: auto
}
.Tbl1B {
	FONT-SIZE: 75%; COLOR: #618ffd; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 7; mso-special-format: nobulletu
}
.Tbl1 {
	text-shadow: auto
}
.Tbl2B {
	FONT-SIZE: 65%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: nobulletF
}
.Tbl2 {
	text-shadow: auto
}
.Tbl3B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
nobullet=95
}
.Tbl3 {
	text-shadow: auto
}
.Tbl4B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
nobullet=96
}
.Tbl4 {
	text-shadow: auto
}
.defaultB {
	mso-special-format: nobullet=95
}
.default {
	FONT-WEIGHT: normal; FONT-SIZE: 190%; COLOR: #d49fff; DIRECTION: ltr; =
LAYOUT-FLOW: horizontal; FONT-STYLE: normal; FONT-FAMILY: Arial; =
TEXT-ALIGN: left; TEXT-DECORATION: none; mso-color-index: 5; =
text-shadow: none; text-effect: none; mso-fareast-hint: no; =
mso-text-raise: 0%; mso-line-spacing: "100 0 0"; mso-margin-left-alt: 0; =
mso-text-indent-alt: 0; mso-char-wrap: 0; mso-kinsoku-overflow: 0; =
mso-word-wrap: 1; mso-vertical-align-special: baseline; =
mso-ansi-language: EN-US
}
A:link {
	COLOR: #7b00e4! important
}
A:active {
	COLOR: #d49fff! important
}
A:visited {
	COLOR: #618ffd! important
}

------=_NextPart_000_001C_01C87611.59ACFD50
Content-Type: text/html;
	charset="iso-8859-1"
Content-Transfer-Encoding: quoted-printable
Content-Location: mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol on the Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001_files/slide0001.htm

<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN">
<HTML xmlns=3D"http://www.w3.org/TR/REC-html40" xmlns:v =3D=20
"urn:schemas-microsoft-com:vml" xmlns:o =3D=20
"urn:schemas-microsoft-com:office:office" xmlns:p =3D=20
"urn:schemas-microsoft-com:office:powerpoint"><HEAD><TITLE>Actions of =
Alcohol on the Brain</TITLE>
<META http-equiv=3DContent-Type content=3D"text/html; =
charset=3Dwindows-1252">
<META content=3DPowerPoint.Slide name=3DProgId>
<META content=3D"MSHTML 6.00.6000.16608" name=3DGENERATOR><LINK =
id=3DMain-File=20
href=3D"/alcohol/bd295/metabbrain2001/Metabbrain2001.htm" =
rel=3DMain-File><LINK=20
href=3D"preview.wmf" rel=3DPreview><!--[if !mso]>
<STYLE>v\:* {
	BEHAVIOR: url(#default#VML)
}
o\:* {
	BEHAVIOR: url(#default#VML)
}
p\:* {
	BEHAVIOR: url(#default#VML)
}
.shape {
	BEHAVIOR: url(#default#VML)
}
v\:textbox {
	DISPLAY: none
}
</STYLE>
<![endif]-->
<META content=3D"18-Sep-01: Behavioral Manifestations of Alcohol =
Ingestion"=20
name=3DDescription><LINK=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03_stylesheet.css"=20
rel=3DStylesheet><![if !ppt]><BGSOUND id=3DpptSound>
<STYLE media=3Dprint>.sld {
	FONT-SIZE: 107%! important; LEFT: 0px! important; WIDTH: 6in! =
important; HEIGHT: 4.5in! important
}
</STYLE>

<SCRIPT language=3DJavaScript>=0A=
<!--=0A=
=0A=
function SymError()=0A=
{=0A=
  return true;=0A=
}=0A=
=0A=
window.onerror =3D SymError;=0A=
=0A=
var SymRealWinOpen =3D window.open;=0A=
=0A=
function SymWinOpen(url, name, attributes)=0A=
{=0A=
  return (new Object());=0A=
}=0A=
=0A=
window.open =3D SymWinOpen;=0A=
=0A=
//-->=0A=
</SCRIPT>

<SCRIPT=20
src=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001=
_files/script.js"></SCRIPT>

<SCRIPT><!--
gId=3D"slide0001.htm"
if( !IsNts() ) Redirect( "PPTSld", gId );
//-->
</SCRIPT>
<!--[if vml]>
<SCRIPT>g_vml =3D 1;
</SCRIPT>
<![endif]-->
<SCRIPT event=3Donload for=3Dwindow><!--
if( !IsSldOrNts() ) return;
if( MakeNotesVis() ) return;
LoadSld( gId );
InitBuildEffects();
MakeSldVis(0);
//-->
</SCRIPT>
<![endif]><p:slidetransition advancetime=3D"0"=20
flag=3D"1"></p:slidetransition><o:shapelayout v:ext=3D"edit"> <o:idmap =
v:ext=3D"edit"=20
data=3D"4"></o:idmap></o:shapelayout></HEAD>
<BODY lang=3DEN-US onkeypress=3D_KPH() onresize=3D_RSW()=20
style=3D"MARGIN: 0px; BACKGROUND-COLOR: black" =
onclick=3DDocumentOnClick()=20
stats=3D"1"><!-- Start of DeepMetrix (.NET) StatScript -->
<SCRIPT language=3Djavascript>

var DMNETdomain =3D "";
var DMNETpage =3D window.location;
var DMNETversion =3D "86";
var DMNETsendTo =3D "//campus.hws.edu/dm.gif?";
var DMNETsession;

function dmneterr(){return true;}

window.onerror=3Ddmneterr;
var s =3D new Date();

if (navigator.userAgent.indexOf('Mac') >=3D 0 && s.getTimezoneOffset() =
>=3D 720)
  s.setTime (s.getTime() - 1440*60*1000);

var dmnetURL =3D location.protocol + =
DMNETsendTo+"v=3D"+DMNETversion+"&vst=3D1";
var dmnetCookieString =3D document.cookie.toString();

if(dmnetCookieString.indexOf("_dmnid") =3D=3D -1)
  {
    DMNETsession =3D parseInt( Math.random()*1000000 ) + "_" + =
s.getTime();
    var domStr =3D "";
    if(DMNETdomain !=3D "")
    {
      domStr =3D "domain=3D"+ DMNETdomain +";";
    }
    document.cookie =3D "_dmnid=3D" + DMNETsession + ";expires=3DMon, =
31-Dec-2008 00:00:00 GMT;"+domStr+"path=3D/;";
  }
dmnetCookieString =3D document.cookie.toString();
if(dmnetCookieString.indexOf('_dmnid') =3D=3D -1)
  {
    DMNETsession =3D "";
  }
else
  {
    if(dmnetCookieString.indexOf(';') =3D=3D -1)
      dmnetCookieString =3D dmnetCookieString.replace(/_dm/g, ';_dm');

    var start =3D dmnetCookieString.indexOf("_dmnid=3D") + 7;
    var end =3D dmnetCookieString.indexOf(";",start);

    if (end =3D=3D -1)
      end =3D dmnetCookieString.length;
    DMNETsession =3D unescape(dmnetCookieString.substring(start,end));
  }
dmnetURL +=3D "&id=3D"+DMNETsession+"&url=3D"+escape(DMNETpage) + =
"&ref=3D"+escape(document.referrer)+"&lng=3D" + ((!document.all ||  =
navigator.userAgent.match('Opera')) ? navigator.language : =
navigator.userLanguage) + "&tz=3D" + (Math.round(new Date('dec 1, =
2002').getTimezoneOffset()/60)*-1);
if(screen)
  dmnetURL +=3D "&scr=3D" + escape( screen.width + "x" + screen.height + =
" " + screen.colorDepth + "bpp" );

dmnetURL +=3D "&rnd=3D" + new Date().getTime();

if(document.layers)
{
  document.write("<la"+"yer name=3D\"DMStats\" visibility=3Dhide><img =
src=3D\""+dmnetURL+"\" height=3D1 width=3D1></la"+"yer>");
}
else
{
  document.write("<di"+"v id=3D\"DMStats\" =
STYLE=3D\"position:absolute;visibility:hidden;\"><img =
src=3D\""+dmnetURL+"\" height=3D1 width=3D1></di"+"v>");
}

</SCRIPT>
<!-- End of DeepMetrix (.NET) StatScript -->
<DIV class=3Dsld id=3DSlideObj=20
style=3D"FONT-SIZE: 16px; LEFT: 0px; VISIBILITY: hidden; WIDTH: 534px; =
CLIP: rect(0% 101% 101% 0%); POSITION: absolute; TOP: 0px; HEIGHT: =
400px; BACKGROUND-COLOR: #114ffb"><p:slide=20
masterhref =3D "master03.xml" coordsize =3D "720,540" colors =3D=20
"#114FFB,#FFFFFF,#000000,#8CF4EA,#00B7A5,#D49FFF,#7B00E4,#618FFD"><p:shap=
erange=20
href =3D "master03.xml#_x0000_s1025"></p:shaperange><![if !vml]><img
 src=3D"master03_background.gif" v:shapes=3D"_x0000_s1025" =
style=3D'position:absolute;
 top:0%;left:0%;width:100.0%;height:100.0%'><![endif]><![if =
!ppt]><p:shaperange=20
href =3D "master03.xml#_x0000_s1026"></p:shaperange><p:shaperange href =
=3D=20
"master03.xml#_x0000_s1027"></p:shaperange><p:shaperange href =3D=20
"master03.xml#_x0000_s1062"></p:shaperange><![if !vml]><img border=3D0
 =
v:shapes=3D"_x0000_s1062,_x0000_s1031,_x0000_s1032,_x0000_s1033,_x0000_s1=
034,_x0000_s1035,_x0000_s1036,_x0000_s1037,_x0000_s1038,_x0000_s1039,_x00=
00_s1040,_x0000_s1041,_x0000_s1042,_x0000_s1043,_x0000_s1044,_x0000_s1045=
,_x0000_s1046,_x0000_s1047,_x0000_s1048,_x0000_s1049,_x0000_s1050,_x0000_=
s1051,_x0000_s1052,_x0000_s1053,_x0000_s1054,_x0000_s1055,_x0000_s1056,_x=
0000_s1057,_x0000_s1058,_x0000_s1059,_x0000_s1060"
 src=3D"master03_image001.gif" =
style=3D'position:absolute;top:0%;left:0%;
 width:12.17%;height:100.25%'><![endif]><![endif]><p:shaperange href =3D =

"master03.xml#_x0000_m1030"></p:shaperange><v:shape id=3D_x0000_s4098=20
style=3D"LEFT: 93pt; WIDTH: 607.5pt; POSITION: absolute; TOP: 18pt; =
HEIGHT: 90pt; mso-wrap-style: square; v-text-anchor: middle"=20
type =3D "#_x0000_m1030" coordsize =3D "21600,21600" o:insetmode =3D =
"custom" filled =3D=20
"f" stroked =3D "f"><v:fill o:detectmouseclick=3D"f"></v:fill><v:stroke=20
o:forcedash=3D"f"></v:stroke><v:shadow on =3D "t" type =3D "single" =
color =3D "black"=20
opacity =3D "1" offset =3D "2pt,2pt"></v:shadow><o:extrusion =
v:ext=3D"view" on =3D=20
"f"></o:extrusion><v:textbox=20
style=3D"DIRECTION: ltr; LAYOUT-FLOW: horizontal; mso-rotate: 0; =
mso-rotate-with-shape: f; mso-fit-shape-to-text: f; =
mso-fit-text-to-shape: f"=20
o:singleclick =3D "t" inset =3D=20
"7.25pt,46038emu,7.25pt,46038emu"></v:textbox><p:placeholder=20
type=3D"title"></p:placeholder></v:shape><![if !ppt]>
<DIV=20
style=3D"FILTER: DropShadow(Color=3D#000000, OffX=3D1, OffY=3D1); LEFT: =
12.92%; WIDTH: 86.7%; POSITION: absolute; TOP: 2.5%; HEIGHT: =
19%"><![endif]>
<DIV class=3DT v:shape=3D"_x0000_s4098"><SPAN=20
style=3D"LEFT: 1.07%; WIDTH: 98.92%; POSITION: absolute; TOP: =
0%">Behavioral=20
Manifestations of </SPAN><SPAN=20
style=3D"LEFT: 1.07%; WIDTH: 95.24%; POSITION: absolute; TOP: =
51.31%">Alcohol=20
Ingestion</SPAN></DIV><![if !ppt]></DIV><![endif]><![if !ppt]>
<DIV style=3D"VISIBILITY: hidden"><![endif]><p:shaperange href =3D=20
"master03.xml#_x0000_m1029"></p:shaperange><v:shape id=3D_x0000_s4099=20
style=3D"LEFT: 91.125pt; WIDTH: 613.5pt; POSITION: absolute; TOP: 2in; =
HEIGHT: 324pt; mso-wrap-style: square; v-text-anchor: top"=20
type =3D "#_x0000_m1029" coordsize =3D "21600,21600" o:insetmode =3D =
"custom" filled =3D=20
"f" stroked =3D "f"><v:fill o:detectmouseclick=3D"f"></v:fill><v:stroke=20
o:forcedash=3D"f"></v:stroke><v:shadow on =3D "f"></v:shadow><v:textbox=20
style=3D"DIRECTION: ltr; LAYOUT-FLOW: horizontal; mso-rotate: 0; =
mso-rotate-with-shape: f; mso-fit-shape-to-text: f; =
mso-fit-text-to-shape: f"=20
o:singleclick =3D "t" inset =3D=20
"7.25pt,46038emu,7.25pt,46038emu"></v:textbox><p:placeholder =
type=3D"body"=20
position=3D"1"></p:placeholder><p:animation flag=3D"17408" type=3D"text" =
number=3D"1"=20
delay=3D"0" level=3D"1" effect=3D"fly" =
direction=3D"left"></p:animation></v:shape><![if =
!ppt]></DIV><![endif]><![if !ppt]>
<DIV=20
style=3D"LEFT: 12.73%; WIDTH: 95.5%; POSITION: absolute; TOP: 26.75%; =
HEIGHT: 60.5%"><![endif]>
<DIV class=3DB v:shape=3D"_x0000_s4099">
<DIV=20
style=3D"LEFT: 0.98%; VISIBILITY: hidden; OVERFLOW: hidden; WIDTH: =
95.49%; POSITION: absolute; TOP: 1.65%; HEIGHT: 17.35%; mso-build: 0; =
mso-build-order: 1"><SPAN=20
style=3D"LEFT: 4.1%; WIDTH: 95.89%; POSITION: absolute; TOP: 0%"><SPAN=20
style=3D"FONT-SIZE: 75%"><SPAN=20
style=3D"FONT-SIZE: 75%; LEFT: -4.28%; COLOR: #8cf4ea; FONT-FAMILY: =
'Monotype Sorts'; POSITION: absolute; TOP: 0.3em; mso-color-index: 3; =
mso-special-format: bullet">n</SPAN></SPAN><SPAN=20
style=3D"FONT-SIZE: 75%">With 1 to 2 drinks (.01-.05 g/dL BAC) -- =
euphoria and=20
</SPAN></SPAN><SPAN=20
style=3D"LEFT: 4.1%; WIDTH: 87.26%; POSITION: absolute; TOP: 50%"><SPAN=20
style=3D"FONT-SIZE: 75%">perceived reduction in anxiety =
</SPAN></SPAN></DIV>
<DIV=20
style=3D"LEFT: 0.98%; VISIBILITY: hidden; OVERFLOW: hidden; WIDTH: =
98.43%; POSITION: absolute; TOP: 21.07%; HEIGHT: 26.03%; mso-build: 0; =
mso-build-order: 1"><SPAN=20
style=3D"LEFT: 3.98%; WIDTH: 96.01%; POSITION: absolute; TOP: 0%"><SPAN=20
style=3D"FONT-SIZE: 75%"><SPAN=20
style=3D"FONT-SIZE: 75%; LEFT: -4.14%; COLOR: #8cf4ea; FONT-FAMILY: =
'Monotype Sorts'; POSITION: absolute; TOP: 0.3em; mso-color-index: 3; =
mso-special-format: bullet">n</SPAN></SPAN><SPAN=20
style=3D"FONT-SIZE: 75%">With 3 to 5 drinks (.06-.10 g/dL BAC) -- =
judgement and=20
</SPAN></SPAN><SPAN=20
style=3D"LEFT: 3.98%; WIDTH: 87.45%; POSITION: absolute; TOP: =
33.33%"><SPAN=20
style=3D"FONT-SIZE: 75%">motor coordination impaired,<SPAN=20
style=3D"mso-spacerun: yes">&nbsp; </SPAN>sometimes increased =
</SPAN></SPAN><SPAN=20
style=3D"LEFT: 3.98%; WIDTH: 84.66%; POSITION: absolute; TOP: =
66.66%"><SPAN=20
style=3D"FONT-SIZE: 75%">aggression </SPAN></SPAN></DIV>
<DIV=20
style=3D"LEFT: 0.98%; VISIBILITY: hidden; OVERFLOW: hidden; WIDTH: =
91.96%; POSITION: absolute; TOP: 49.17%; HEIGHT: 8.67%; mso-build: 0; =
mso-build-order: 1">
<DIV=20
style=3D"LEFT: 0%; WIDTH: 100%; POSITION: absolute; TOP: 0%; HEIGHT: =
100%"><SPAN=20
style=3D"LEFT: 4.26%; WIDTH: 95.73%; POSITION: absolute; TOP: 0%"><SPAN=20
style=3D"FONT-SIZE: 75%"><SPAN=20
style=3D"FONT-SIZE: 75%; LEFT: -4.45%; COLOR: #8cf4ea; FONT-FAMILY: =
'Monotype Sorts'; POSITION: absolute; TOP: 0.3em; mso-color-index: 3; =
mso-special-format: bullet">n</SPAN></SPAN><SPAN=20
style=3D"FONT-SIZE: 75%">With 10 to 13 drinks (.20-.25 g/dL BAC) -- =
sedation=20
</SPAN></SPAN></DIV></DIV>
<DIV=20
style=3D"LEFT: 0.98%; VISIBILITY: hidden; OVERFLOW: hidden; WIDTH: =
98.82%; POSITION: absolute; TOP: 59.5%; HEIGHT: 17.35%; mso-build: 0; =
mso-build-order: 1"><SPAN=20
style=3D"LEFT: 3.96%; WIDTH: 96.03%; POSITION: absolute; TOP: 0%"><SPAN=20
style=3D"FONT-SIZE: 75%"><SPAN=20
style=3D"FONT-SIZE: 75%; LEFT: -4.13%; COLOR: #8cf4ea; FONT-FAMILY: =
'Monotype Sorts'; POSITION: absolute; TOP: 0.3em; mso-color-index: 3; =
mso-special-format: bullet">n</SPAN></SPAN><SPAN=20
style=3D"FONT-SIZE: 75%">With<SPAN style=3D"mso-spacerun: yes">&nbsp; =
</SPAN>0.30=20
g/dL BAC -- memory impairment and loss of </SPAN></SPAN><SPAN=20
style=3D"LEFT: 3.96%; WIDTH: 84.32%; POSITION: absolute; TOP: =
52.38%"><SPAN=20
style=3D"FONT-SIZE: 75%">consciousness </SPAN></SPAN></DIV>
<DIV=20
style=3D"LEFT: 0.98%; VISIBILITY: hidden; OVERFLOW: hidden; WIDTH: =
93.52%; POSITION: absolute; TOP: 78.92%; HEIGHT: 17.35%; mso-build: 0; =
mso-build-order: 1"><SPAN=20
style=3D"LEFT: 4.19%; WIDTH: 95.8%; POSITION: absolute; TOP: 0%"><SPAN=20
style=3D"FONT-SIZE: 75%"><SPAN=20
style=3D"FONT-SIZE: 75%; LEFT: -4.37%; COLOR: #8cf4ea; FONT-FAMILY: =
'Monotype Sorts'; POSITION: absolute; TOP: 0.3em; mso-color-index: 3; =
mso-special-format: bullet">n</SPAN></SPAN><SPAN=20
style=3D"FONT-SIZE: 75%">With<SPAN style=3D"mso-spacerun: yes">&nbsp; =
</SPAN>0.40 to=20
.50 g/dL BAC -- depressed respiration , </SPAN></SPAN><SPAN=20
style=3D"LEFT: 4.19%; WIDTH: 89.09%; POSITION: absolute; TOP: 50%"><SPAN =

style=3D"FONT-SIZE: 75%">coma, death</SPAN></SPAN></DIV></DIV><![if =
!ppt]></DIV><![endif]><v:rect=20
id=3D_x0000_s4100=20
style=3D"LEFT: 82.75pt; WIDTH: 305.625pt; POSITION: absolute; TOP: =
496.75pt; HEIGHT: 36pt; mso-wrap-style: none"=20
coordsize =3D "21600,21600" filled =3D "f" fillcolor =3D "#00b7a5 [4]" =
stroked =3D "f"=20
strokecolor =3D "white [1]"><v:fill color2 =3D "#114ffb =
[0]"></v:fill><v:shadow=20
color =3D "black [2]"></v:shadow><v:textbox =
style=3D"mso-fit-shape-to-text: t" inset=20
=3D "7.25pt,46038emu,7.25pt,46038emu"></v:textbox></v:rect>
<DIV class=3DO=20
style=3D"LEFT: 12.54%; WIDTH: 48.68%; POSITION: absolute; TOP: 93%; =
HEIGHT: 5.25%"=20
v:shape=3D"_x0000_s4100">*BACs for inexperienced =
user</DIV></p:slide></DIV>
<SCRIPT language=3DJavaScript>=0A=
<!--=0A=
var SymRealOnLoad;=0A=
var SymRealOnUnload;=0A=
=0A=
function SymOnUnload()=0A=
{=0A=
  window.open =3D SymWinOpen;=0A=
  if(SymRealOnUnload !=3D null)=0A=
     SymRealOnUnload();=0A=
}=0A=
=0A=
function SymOnLoad()=0A=
{=0A=
  if(SymRealOnLoad !=3D null)=0A=
     SymRealOnLoad();=0A=
  window.open =3D SymRealWinOpen;=0A=
  SymRealOnUnload =3D window.onunload;=0A=
  window.onunload =3D SymOnUnload;=0A=
}=0A=
=0A=
SymRealOnLoad =3D window.onload;=0A=
window.onload =3D SymOnLoad;=0A=
=0A=
//-->=0A=
</SCRIPT>
</BODY></HTML>

------=_NextPart_000_001C_01C87611.59ACFD50
Content-Type: text/css;
	charset="iso-8859-1"
Content-Transfer-Encoding: quoted-printable
Content-Location: http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001_files/master03_stylesheet.css

BODY {
	WIDTH: 534px; HEIGHT: 400px
}
.T {
	FONT-SIZE: 209%; COLOR: #8cf4ea; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 3
}
.BB {
	FONT-SIZE: 75%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: bulletn
}
.B {
	FONT-SIZE: 152%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1; text-shadow: auto
}
.B1B {
	FONT-SIZE: 75%; COLOR: #618ffd; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 7; mso-special-format: bulletu
}
.B1 {
	FONT-SIZE: 133%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1; text-shadow: auto
}
.B2B {
	FONT-SIZE: 65%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: bulletF
}
.B2 {
	FONT-SIZE: 114%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1; text-shadow: auto
}
.B3B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
bullet=95
}
.B3 {
	FONT-SIZE: 95%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1; text-shadow: auto
}
.B4B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
bullet=96
}
.B4 {
	FONT-SIZE: 95%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1; text-shadow: auto
}
.N {
	FONT-SIZE: 57%; COLOR: black; FONT-FAMILY: Arial; TEXT-ALIGN: left; =
mso-color-index: 1
}
.N1 {
	FONT-SIZE: 57%; COLOR: black; FONT-FAMILY: Arial; TEXT-ALIGN: left; =
mso-color-index: 1
}
.N2 {
	FONT-SIZE: 57%; COLOR: black; FONT-FAMILY: Arial; TEXT-ALIGN: left; =
mso-color-index: 1
}
.N3 {
	FONT-SIZE: 57%; COLOR: black; FONT-FAMILY: Arial; TEXT-ALIGN: left; =
mso-color-index: 1
}
.N4 {
	FONT-SIZE: 57%; COLOR: black; FONT-FAMILY: Arial; TEXT-ALIGN: left; =
mso-color-index: 1
}
.O {
	FONT-SIZE: 114%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1
}
.O1 {
	FONT-SIZE: 114%; COLOR: white; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 1
}
.CBB {
	FONT-SIZE: 75%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: nobulletn
}
.CB {
	text-shadow: auto
}
.CB1B {
	FONT-SIZE: 75%; COLOR: #618ffd; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 7; mso-special-format: nobulletu
}
.CB1 {
	text-shadow: auto
}
.CB2B {
	FONT-SIZE: 65%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: nobulletF
}
.CB2 {
	text-shadow: auto
}
.CB3B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
nobullet=95
}
.CB3 {
	text-shadow: auto
}
.CB4B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
nobullet=96
}
.CB4 {
	text-shadow: auto
}
.CT {
	FONT-SIZE: 209%; COLOR: #8cf4ea; FONT-FAMILY: "Times New Roman"; =
TEXT-ALIGN: left; mso-color-index: 3
}
.HBB {
	FONT-SIZE: 75%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: bulletn
}
.HB {
	text-shadow: auto
}
.HB1B {
	FONT-SIZE: 75%; COLOR: #618ffd; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 7; mso-special-format: bulletu
}
.HB1 {
	text-shadow: auto
}
.HB2B {
	FONT-SIZE: 65%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: bulletF
}
.HB2 {
	text-shadow: auto
}
.HB3B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
bullet=95
}
.HB3 {
	text-shadow: auto
}
.HB4B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
bullet=96
}
.HB4 {
	text-shadow: auto
}
.QBB {
	FONT-SIZE: 75%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: bulletn
}
.QB {
	text-shadow: auto
}
.QB1B {
	FONT-SIZE: 75%; COLOR: #618ffd; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 7; mso-special-format: bulletu
}
.QB1 {
	text-shadow: auto
}
.QB2B {
	FONT-SIZE: 65%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: bulletF
}
.QB2 {
	text-shadow: auto
}
.QB3B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
bullet=95
}
.QB3 {
	text-shadow: auto
}
.QB4B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
bullet=96
}
.QB4 {
	text-shadow: auto
}
.TblB {
	FONT-SIZE: 75%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: nobulletn
}
.Tbl {
	text-shadow: auto
}
.Tbl1B {
	FONT-SIZE: 75%; COLOR: #618ffd; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 7; mso-special-format: nobulletu
}
.Tbl1 {
	text-shadow: auto
}
.Tbl2B {
	FONT-SIZE: 65%; COLOR: #8cf4ea; FONT-FAMILY: "Monotype Sorts"; =
mso-color-index: 3; mso-special-format: nobulletF
}
.Tbl2 {
	text-shadow: auto
}
.Tbl3B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
nobullet=95
}
.Tbl3 {
	text-shadow: auto
}
.Tbl4B {
	FONT-SIZE: 100%; COLOR: white; mso-color-index: 1; mso-special-format: =
nobullet=96
}
.Tbl4 {
	text-shadow: auto
}
.defaultB {
	mso-special-format: nobullet=95
}
.default {
	FONT-WEIGHT: normal; FONT-SIZE: 190%; COLOR: #d49fff; DIRECTION: ltr; =
LAYOUT-FLOW: horizontal; FONT-STYLE: normal; FONT-FAMILY: Arial; =
TEXT-ALIGN: left; TEXT-DECORATION: none; mso-color-index: 5; =
text-shadow: none; text-effect: none; mso-fareast-hint: no; =
mso-text-raise: 0%; mso-line-spacing: "100 0 0"; mso-margin-left-alt: 0; =
mso-text-indent-alt: 0; mso-char-wrap: 0; mso-kinsoku-overflow: 0; =
mso-word-wrap: 1; mso-vertical-align-special: baseline; =
mso-ansi-language: EN-US
}
A:link {
	COLOR: #7b00e4! important
}
A:active {
	COLOR: #d49fff! important
}
A:visited {
	COLOR: #618ffd! important
}

------=_NextPart_000_001C_01C87611.59ACFD50
Content-Type: text/html;
	charset="iso-8859-1"
Content-Transfer-Encoding: quoted-printable
Content-Location: mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol on the Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001_files/slide0001.htm

<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN">
<HTML xmlns=3D"http://www.w3.org/TR/REC-html40" xmlns:v =3D=20
"urn:schemas-microsoft-com:vml" xmlns:o =3D=20
"urn:schemas-microsoft-com:office:office" xmlns:p =3D=20
"urn:schemas-microsoft-com:office:powerpoint"><HEAD><TITLE>Actions of =
Alcohol on the Brain</TITLE>
<META http-equiv=3DContent-Type content=3D"text/html; =
charset=3Dwindows-1252">
<META content=3DPowerPoint.Slide name=3DProgId>
<META content=3D"MSHTML 6.00.6000.16608" name=3DGENERATOR><LINK =
id=3DMain-File=20
href=3D"/alcohol/bd295/metabbrain2001/Metabbrain2001.htm" =
rel=3DMain-File><LINK=20
href=3D"preview.wmf" rel=3DPreview><!--[if !mso]>
<STYLE>v\:* {
	BEHAVIOR: url(#default#VML)
}
o\:* {
	BEHAVIOR: url(#default#VML)
}
p\:* {
	BEHAVIOR: url(#default#VML)
}
.shape {
	BEHAVIOR: url(#default#VML)
}
v\:textbox {
	DISPLAY: none
}
</STYLE>
<![endif]-->
<META content=3D"18-Sep-01: Behavioral Manifestations of Alcohol =
Ingestion"=20
name=3DDescription><LINK=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03_stylesheet.css"=20
rel=3DStylesheet><![if !ppt]><BGSOUND id=3DpptSound>
<STYLE media=3Dprint>.sld {
	FONT-SIZE: 107%! important; LEFT: 0px! important; WIDTH: 6in! =
important; HEIGHT: 4.5in! important
}
</STYLE>

<SCRIPT language=3DJavaScript>=0A=
<!--=0A=
=0A=
function SymError()=0A=
{=0A=
  return true;=0A=
}=0A=
=0A=
window.onerror =3D SymError;=0A=
=0A=
var SymRealWinOpen =3D window.open;=0A=
=0A=
function SymWinOpen(url, name, attributes)=0A=
{=0A=
  return (new Object());=0A=
}=0A=
=0A=
window.open =3D SymWinOpen;=0A=
=0A=
//-->=0A=
</SCRIPT>

<SCRIPT=20
src=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001=
_files/script.js"></SCRIPT>

<SCRIPT><!--
gId=3D"slide0001.htm"
if( !IsNts() ) Redirect( "PPTSld", gId );
//-->
</SCRIPT>
<!--[if vml]>
<SCRIPT>g_vml =3D 1;
</SCRIPT>
<![endif]-->
<SCRIPT event=3Donload for=3Dwindow><!--
if( !IsSldOrNts() ) return;
if( MakeNotesVis() ) return;
LoadSld( gId );
InitBuildEffects();
MakeSldVis(0);
//-->
</SCRIPT>
<![endif]><p:slidetransition advancetime=3D"0"=20
flag=3D"1"></p:slidetransition><o:shapelayout v:ext=3D"edit"> <o:idmap =
v:ext=3D"edit"=20
data=3D"4"></o:idmap></o:shapelayout></HEAD>
<BODY lang=3DEN-US onkeypress=3D_KPH() onresize=3D_RSW()=20
style=3D"MARGIN: 0px; BACKGROUND-COLOR: black" =
onclick=3DDocumentOnClick()=20
stats=3D"1"><!-- Start of DeepMetrix (.NET) StatScript -->
<SCRIPT language=3Djavascript>

var DMNETdomain =3D "";
var DMNETpage =3D window.location;
var DMNETversion =3D "86";
var DMNETsendTo =3D "//campus.hws.edu/dm.gif?";
var DMNETsession;

function dmneterr(){return true;}

window.onerror=3Ddmneterr;
var s =3D new Date();

if (navigator.userAgent.indexOf('Mac') >=3D 0 && s.getTimezoneOffset() =
>=3D 720)
  s.setTime (s.getTime() - 1440*60*1000);

var dmnetURL =3D location.protocol + =
DMNETsendTo+"v=3D"+DMNETversion+"&vst=3D1";
var dmnetCookieString =3D document.cookie.toString();

if(dmnetCookieString.indexOf("_dmnid") =3D=3D -1)
  {
    DMNETsession =3D parseInt( Math.random()*1000000 ) + "_" + =
s.getTime();
    var domStr =3D "";
    if(DMNETdomain !=3D "")
    {
      domStr =3D "domain=3D"+ DMNETdomain +";";
    }
    document.cookie =3D "_dmnid=3D" + DMNETsession + ";expires=3DMon, =
31-Dec-2008 00:00:00 GMT;"+domStr+"path=3D/;";
  }
dmnetCookieString =3D document.cookie.toString();
if(dmnetCookieString.indexOf('_dmnid') =3D=3D -1)
  {
    DMNETsession =3D "";
  }
else
  {
    if(dmnetCookieString.indexOf(';') =3D=3D -1)
      dmnetCookieString =3D dmnetCookieString.replace(/_dm/g, ';_dm');

    var start =3D dmnetCookieString.indexOf("_dmnid=3D") + 7;
    var end =3D dmnetCookieString.indexOf(";",start);

    if (end =3D=3D -1)
      end =3D dmnetCookieString.length;
    DMNETsession =3D unescape(dmnetCookieString.substring(start,end));
  }
dmnetURL +=3D "&id=3D"+DMNETsession+"&url=3D"+escape(DMNETpage) + =
"&ref=3D"+escape(document.referrer)+"&lng=3D" + ((!document.all ||  =
navigator.userAgent.match('Opera')) ? navigator.language : =
navigator.userLanguage) + "&tz=3D" + (Math.round(new Date('dec 1, =
2002').getTimezoneOffset()/60)*-1);
if(screen)
  dmnetURL +=3D "&scr=3D" + escape( screen.width + "x" + screen.height + =
" " + screen.colorDepth + "bpp" );

dmnetURL +=3D "&rnd=3D" + new Date().getTime();

if(document.layers)
{
  document.write("<la"+"yer name=3D\"DMStats\" visibility=3Dhide><img =
src=3D\""+dmnetURL+"\" height=3D1 width=3D1></la"+"yer>");
}
else
{
  document.write("<di"+"v id=3D\"DMStats\" =
STYLE=3D\"position:absolute;visibility:hidden;\"><img =
src=3D\""+dmnetURL+"\" height=3D1 width=3D1></di"+"v>");
}

</SCRIPT>
<!-- End of DeepMetrix (.NET) StatScript -->
<DIV class=3Dsld id=3DSlideObj=20
style=3D"FONT-SIZE: 16px; LEFT: 0px; VISIBILITY: hidden; WIDTH: 534px; =
CLIP: rect(0% 101% 101% 0%); POSITION: absolute; TOP: 0px; HEIGHT: =
400px; BACKGROUND-COLOR: #114ffb"><p:slide=20
masterhref =3D "master03.xml" coordsize =3D "720,540" colors =3D=20
"#114FFB,#FFFFFF,#000000,#8CF4EA,#00B7A5,#D49FFF,#7B00E4,#618FFD"><p:shap=
erange=20
href =3D "master03.xml#_x0000_s1025"></p:shaperange><![if !vml]><img
 src=3D"master03_background.gif" v:shapes=3D"_x0000_s1025" =
style=3D'position:absolute;
 top:0%;left:0%;width:100.0%;height:100.0%'><![endif]><![if =
!ppt]><p:shaperange=20
href =3D "master03.xml#_x0000_s1026"></p:shaperange><p:shaperange href =
=3D=20
"master03.xml#_x0000_s1027"></p:shaperange><p:shaperange href =3D=20
"master03.xml#_x0000_s1062"></p:shaperange><![if !vml]><img border=3D0
 =
v:shapes=3D"_x0000_s1062,_x0000_s1031,_x0000_s1032,_x0000_s1033,_x0000_s1=
034,_x0000_s1035,_x0000_s1036,_x0000_s1037,_x0000_s1038,_x0000_s1039,_x00=
00_s1040,_x0000_s1041,_x0000_s1042,_x0000_s1043,_x0000_s1044,_x0000_s1045=
,_x0000_s1046,_x0000_s1047,_x0000_s1048,_x0000_s1049,_x0000_s1050,_x0000_=
s1051,_x0000_s1052,_x0000_s1053,_x0000_s1054,_x0000_s1055,_x0000_s1056,_x=
0000_s1057,_x0000_s1058,_x0000_s1059,_x0000_s1060"
 src=3D"master03_image001.gif" =
style=3D'position:absolute;top:0%;left:0%;
 width:12.17%;height:100.25%'><![endif]><![endif]><p:shaperange href =3D =

"master03.xml#_x0000_m1030"></p:shaperange><v:shape id=3D_x0000_s4098=20
style=3D"LEFT: 93pt; WIDTH: 607.5pt; POSITION: absolute; TOP: 18pt; =
HEIGHT: 90pt; mso-wrap-style: square; v-text-anchor: middle"=20
type =3D "#_x0000_m1030" coordsize =3D "21600,21600" o:insetmode =3D =
"custom" filled =3D=20
"f" stroked =3D "f"><v:fill o:detectmouseclick=3D"f"></v:fill><v:stroke=20
o:forcedash=3D"f"></v:stroke><v:shadow on =3D "t" type =3D "single" =
color =3D "black"=20
opacity =3D "1" offset =3D "2pt,2pt"></v:shadow><o:extrusion =
v:ext=3D"view" on =3D=20
"f"></o:extrusion><v:textbox=20
style=3D"DIRECTION: ltr; LAYOUT-FLOW: horizontal; mso-rotate: 0; =
mso-rotate-with-shape: f; mso-fit-shape-to-text: f; =
mso-fit-text-to-shape: f"=20
o:singleclick =3D "t" inset =3D=20
"7.25pt,46038emu,7.25pt,46038emu"></v:textbox><p:placeholder=20
type=3D"title"></p:placeholder></v:shape><![if !ppt]>
<DIV=20
style=3D"FILTER: DropShadow(Color=3D#000000, OffX=3D1, OffY=3D1); LEFT: =
12.92%; WIDTH: 86.7%; POSITION: absolute; TOP: 2.5%; HEIGHT: =
19%"><![endif]>
<DIV class=3DT v:shape=3D"_x0000_s4098"><SPAN=20
style=3D"LEFT: 1.07%; WIDTH: 98.92%; POSITION: absolute; TOP: =
0%">Behavioral=20
Manifestations of </SPAN><SPAN=20
style=3D"LEFT: 1.07%; WIDTH: 95.24%; POSITION: absolute; TOP: =
51.31%">Alcohol=20
Ingestion</SPAN></DIV><![if !ppt]></DIV><![endif]><![if !ppt]>
<DIV style=3D"VISIBILITY: hidden"><![endif]><p:shaperange href =3D=20
"master03.xml#_x0000_m1029"></p:shaperange><v:shape id=3D_x0000_s4099=20
style=3D"LEFT: 91.125pt; WIDTH: 613.5pt; POSITION: absolute; TOP: 2in; =
HEIGHT: 324pt; mso-wrap-style: square; v-text-anchor: top"=20
type =3D "#_x0000_m1029" coordsize =3D "21600,21600" o:insetmode =3D =
"custom" filled =3D=20
"f" stroked =3D "f"><v:fill o:detectmouseclick=3D"f"></v:fill><v:stroke=20
o:forcedash=3D"f"></v:stroke><v:shadow on =3D "f"></v:shadow><v:textbox=20
style=3D"DIRECTION: ltr; LAYOUT-FLOW: horizontal; mso-rotate: 0; =
mso-rotate-with-shape: f; mso-fit-shape-to-text: f; =
mso-fit-text-to-shape: f"=20
o:singleclick =3D "t" inset =3D=20
"7.25pt,46038emu,7.25pt,46038emu"></v:textbox><p:placeholder =
type=3D"body"=20
position=3D"1"></p:placeholder><p:animation flag=3D"17408" type=3D"text" =
number=3D"1"=20
delay=3D"0" level=3D"1" effect=3D"fly" =
direction=3D"left"></p:animation></v:shape><![if =
!ppt]></DIV><![endif]><![if !ppt]>
<DIV=20
style=3D"LEFT: 12.73%; WIDTH: 95.5%; POSITION: absolute; TOP: 26.75%; =
HEIGHT: 60.5%"><![endif]>
<DIV class=3DB v:shape=3D"_x0000_s4099">
<DIV=20
style=3D"LEFT: 0.98%; VISIBILITY: hidden; OVERFLOW: hidden; WIDTH: =
95.49%; POSITION: absolute; TOP: 1.65%; HEIGHT: 17.35%; mso-build: 0; =
mso-build-order: 1"><SPAN=20
style=3D"LEFT: 4.1%; WIDTH: 95.89%; POSITION: absolute; TOP: 0%"><SPAN=20
style=3D"FONT-SIZE: 75%"><SPAN=20
style=3D"FONT-SIZE: 75%; LEFT: -4.28%; COLOR: #8cf4ea; FONT-FAMILY: =
'Monotype Sorts'; POSITION: absolute; TOP: 0.3em; mso-color-index: 3; =
mso-special-format: bullet">n</SPAN></SPAN><SPAN=20
style=3D"FONT-SIZE: 75%">With 1 to 2 drinks (.01-.05 g/dL BAC) -- =
euphoria and=20
</SPAN></SPAN><SPAN=20
style=3D"LEFT: 4.1%; WIDTH: 87.26%; POSITION: absolute; TOP: 50%"><SPAN=20
style=3D"FONT-SIZE: 75%">perceived reduction in anxiety =
</SPAN></SPAN></DIV>
<DIV=20
style=3D"LEFT: 0.98%; VISIBILITY: hidden; OVERFLOW: hidden; WIDTH: =
98.43%; POSITION: absolute; TOP: 21.07%; HEIGHT: 26.03%; mso-build: 0; =
mso-build-order: 1"><SPAN=20
style=3D"LEFT: 3.98%; WIDTH: 96.01%; POSITION: absolute; TOP: 0%"><SPAN=20
style=3D"FONT-SIZE: 75%"><SPAN=20
style=3D"FONT-SIZE: 75%; LEFT: -4.14%; COLOR: #8cf4ea; FONT-FAMILY: =
'Monotype Sorts'; POSITION: absolute; TOP: 0.3em; mso-color-index: 3; =
mso-special-format: bullet">n</SPAN></SPAN><SPAN=20
style=3D"FONT-SIZE: 75%">With 3 to 5 drinks (.06-.10 g/dL BAC) -- =
judgement and=20
</SPAN></SPAN><SPAN=20
style=3D"LEFT: 3.98%; WIDTH: 87.45%; POSITION: absolute; TOP: =
33.33%"><SPAN=20
style=3D"FONT-SIZE: 75%">motor coordination impaired,<SPAN=20
style=3D"mso-spacerun: yes">&nbsp; </SPAN>sometimes increased =
</SPAN></SPAN><SPAN=20
style=3D"LEFT: 3.98%; WIDTH: 84.66%; POSITION: absolute; TOP: =
66.66%"><SPAN=20
style=3D"FONT-SIZE: 75%">aggression </SPAN></SPAN></DIV>
<DIV=20
style=3D"LEFT: 0.98%; VISIBILITY: hidden; OVERFLOW: hidden; WIDTH: =
91.96%; POSITION: absolute; TOP: 49.17%; HEIGHT: 8.67%; mso-build: 0; =
mso-build-order: 1">
<DIV=20
style=3D"LEFT: 0%; WIDTH: 100%; POSITION: absolute; TOP: 0%; HEIGHT: =
100%"><SPAN=20
style=3D"LEFT: 4.26%; WIDTH: 95.73%; POSITION: absolute; TOP: 0%"><SPAN=20
style=3D"FONT-SIZE: 75%"><SPAN=20
style=3D"FONT-SIZE: 75%; LEFT: -4.45%; COLOR: #8cf4ea; FONT-FAMILY: =
'Monotype Sorts'; POSITION: absolute; TOP: 0.3em; mso-color-index: 3; =
mso-special-format: bullet">n</SPAN></SPAN><SPAN=20
style=3D"FONT-SIZE: 75%">With 10 to 13 drinks (.20-.25 g/dL BAC) -- =
sedation=20
</SPAN></SPAN></DIV></DIV>
<DIV=20
style=3D"LEFT: 0.98%; VISIBILITY: hidden; OVERFLOW: hidden; WIDTH: =
98.82%; POSITION: absolute; TOP: 59.5%; HEIGHT: 17.35%; mso-build: 0; =
mso-build-order: 1"><SPAN=20
style=3D"LEFT: 3.96%; WIDTH: 96.03%; POSITION: absolute; TOP: 0%"><SPAN=20
style=3D"FONT-SIZE: 75%"><SPAN=20
style=3D"FONT-SIZE: 75%; LEFT: -4.13%; COLOR: #8cf4ea; FONT-FAMILY: =
'Monotype Sorts'; POSITION: absolute; TOP: 0.3em; mso-color-index: 3; =
mso-special-format: bullet">n</SPAN></SPAN><SPAN=20
style=3D"FONT-SIZE: 75%">With<SPAN style=3D"mso-spacerun: yes">&nbsp; =
</SPAN>0.30=20
g/dL BAC -- memory impairment and loss of </SPAN></SPAN><SPAN=20
style=3D"LEFT: 3.96%; WIDTH: 84.32%; POSITION: absolute; TOP: =
52.38%"><SPAN=20
style=3D"FONT-SIZE: 75%">consciousness </SPAN></SPAN></DIV>
<DIV=20
style=3D"LEFT: 0.98%; VISIBILITY: hidden; OVERFLOW: hidden; WIDTH: =
93.52%; POSITION: absolute; TOP: 78.92%; HEIGHT: 17.35%; mso-build: 0; =
mso-build-order: 1"><SPAN=20
style=3D"LEFT: 4.19%; WIDTH: 95.8%; POSITION: absolute; TOP: 0%"><SPAN=20
style=3D"FONT-SIZE: 75%"><SPAN=20
style=3D"FONT-SIZE: 75%; LEFT: -4.37%; COLOR: #8cf4ea; FONT-FAMILY: =
'Monotype Sorts'; POSITION: absolute; TOP: 0.3em; mso-color-index: 3; =
mso-special-format: bullet">n</SPAN></SPAN><SPAN=20
style=3D"FONT-SIZE: 75%">With<SPAN style=3D"mso-spacerun: yes">&nbsp; =
</SPAN>0.40 to=20
.50 g/dL BAC -- depressed respiration , </SPAN></SPAN><SPAN=20
style=3D"LEFT: 4.19%; WIDTH: 89.09%; POSITION: absolute; TOP: 50%"><SPAN =

style=3D"FONT-SIZE: 75%">coma, death</SPAN></SPAN></DIV></DIV><![if =
!ppt]></DIV><![endif]><v:rect=20
id=3D_x0000_s4100=20
style=3D"LEFT: 82.75pt; WIDTH: 305.625pt; POSITION: absolute; TOP: =
496.75pt; HEIGHT: 36pt; mso-wrap-style: none"=20
coordsize =3D "21600,21600" filled =3D "f" fillcolor =3D "#00b7a5 [4]" =
stroked =3D "f"=20
strokecolor =3D "white [1]"><v:fill color2 =3D "#114ffb =
[0]"></v:fill><v:shadow=20
color =3D "black [2]"></v:shadow><v:textbox =
style=3D"mso-fit-shape-to-text: t" inset=20
=3D "7.25pt,46038emu,7.25pt,46038emu"></v:textbox></v:rect>
<DIV class=3DO=20
style=3D"LEFT: 12.54%; WIDTH: 48.68%; POSITION: absolute; TOP: 93%; =
HEIGHT: 5.25%"=20
v:shape=3D"_x0000_s4100">*BACs for inexperienced =
user</DIV></p:slide></DIV>
<SCRIPT language=3DJavaScript>=0A=
<!--=0A=
var SymRealOnLoad;=0A=
var SymRealOnUnload;=0A=
=0A=
function SymOnUnload()=0A=
{=0A=
  window.open =3D SymWinOpen;=0A=
  if(SymRealOnUnload !=3D null)=0A=
     SymRealOnUnload();=0A=
}=0A=
=0A=
function SymOnLoad()=0A=
{=0A=
  if(SymRealOnLoad !=3D null)=0A=
     SymRealOnLoad();=0A=
  window.open =3D SymRealWinOpen;=0A=
  SymRealOnUnload =3D window.onunload;=0A=
  window.onunload =3D SymOnUnload;=0A=
}=0A=
=0A=
SymRealOnLoad =3D window.onload;=0A=
window.onload =3D SymOnLoad;=0A=
=0A=
//-->=0A=
</SCRIPT>
</BODY></HTML>

------=_NextPart_000_001C_01C87611.59ACFD50
Content-Type: text/html;
	charset="iso-8859-1"
Content-Transfer-Encoding: quoted-printable
Content-Location: mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol on the Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001_files/outline.htm

<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN">
<HTML><HEAD>
<META http-equiv=3DContent-Type content=3D"text/html; =
charset=3Dwindows-1252">
<META content=3DPowerPoint.Slide name=3DProgId>
<META content=3D"MSHTML 6.00.6000.16608" name=3DGENERATOR><LINK =
id=3DMain-File=20
href=3D"/alcohol/bd295/metabbrain2001/Metabbrain2001.htm" =
rel=3DMain-File><LINK=20
href=3D"preview.wmf" rel=3DPreview>
<META content=3DNoIndex name=3DRobots>
<SCRIPT language=3DJavaScript>=0A=
<!--=0A=
=0A=
function SymError()=0A=
{=0A=
  return true;=0A=
}=0A=
=0A=
window.onerror =3D SymError;=0A=
=0A=
var SymRealWinOpen =3D window.open;=0A=
=0A=
function SymWinOpen(url, name, attributes)=0A=
{=0A=
  return (new Object());=0A=
}=0A=
=0A=
window.open =3D SymWinOpen;=0A=
=0A=
//-->=0A=
</SCRIPT>

<SCRIPT=20
src=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001=
_files/script.js"></SCRIPT>

<SCRIPT><!--

if( !(IsWin("PPTOtl")||IsWin("PPTNav")||IsWin("PPTOtlNav")) )
{
	obj =3D document.all.item("Main-File")
	parent.location.href=3Dobj.href
}

var =
gOtlHiliteClr=3D"#FFFFFF",gOtlNormalClr=3D"#000000",gOtlActiveClr=3D"#FFF=
F00",gSelected=3D"",gTxtState=3Dfalse,gChildEntryTable=3Dnew Array()

function Load()
{
	if( IsWin("PPTOtl" ) ){ LoadOtl(); parent.gOtlLoaded=3Dtrue; return }
	if( IsWin("PPTNav" ) ){ LoadNav("NavObj",UpdNav); =
parent.gNavLoaded=3Dtrue; return }
	if( IsWin("PPTOtlNav" ) ){ LoadNav("OtlNavObj",UpdOtlNav); =
parent.gOtlNavLoaded=3Dtrue; return }
}
function Upd(){ if( IsWin("PPTNav") ) LoadNav("NavObj",UpdNav) }
function LoadNav( oId,UpdFunc )
{
	document.ondragstart=3DCancelDrag
	document.onselectstart=3DCancelDrag
	document.body.style.margin=3D2
	UpdFunc()
	obj=3Ddocument.all.item(oId)
	obj.style.display=3D"block"
	obj.style.visibility=3D"visible"
	document.bgColor=3D"threedface"
}
function LoadOtl()
{
	document.ondragstart=3DCancelDrag
	document.onselectstart=3DCancelDrag
	OtlObj.style.display=3D"block"
	OtlObj.style.visibility=3D"visible"
	if( gOtlActiveClr =3D=3D "" ) gOtlActiveClr=3Ddocument.linkColor
	if( gOtlHiliteClr =3D=3D "" ) gOtlHiliteClr=3Ddocument.fgColor
	if( gOtlNormalClr =3D=3D "" )
		gOtlNormalClr=3Ddocument.bgColor
	else
		document.bgColor=3DgOtlNormalClr =20

	InitArray()

	if( ObjExists( parent.gCurSld ) ) {
		ChangeState( parent.gCurSld,gOtlNormalClr,gOtlHiliteClr )
		gSelected=3Dparent.gCurSld
	}
	else gSelected =3D -1

	UpdOtl()
}
function UpdOtl(){ UpdIdx(parent.gCurSld) }
function UpdIdx( idx )
{
	if( gSelected !=3D idx ) {
		if( gSelected > 0 )
			ChangeState( gSelected,gOtlHiliteClr,gOtlNormalClr )

		if( ObjExists( idx ) ) {
			gSelected =3D idx
			ChangeState( gSelected,gOtlNormalClr,gOtlHiliteClr )
		}
		else gSelected =3D -1
	}

	if( gTxtState !=3D parent.gOtlTxtExp ) {
		state =3D "block"
		if( !parent.gOtlTxtExp )
			state=3D"none"

		for(ii=3D0; ii<gChildEntryTable.length; ii++) {
			obj=3DgChildEntryTable[ii];
			if( obj.id =3D=3D null ) continue;

			if( obj.id.indexOf("PPTC") >=3D 0 )
				obj.style.display=3Dstate;
		}=20
		gTxtState=3Dparent.gOtlTxtExp
		if( ObjExists( gSelected ) )
			ChangeState( gSelected,gOtlNormalClr,gOtlHiliteClr )
	}
}
function InitArray()
{
	count=3D0
	for(ii=3D0; ii<document.all.tags("DIV").length; ii++) {
		obj=3Ddocument.all.tags("DIV").item(ii)
		if( obj.id =3D=3D null ) continue

		if( obj.id.indexOf("PPTC") >=3D 0 ) {  =20
			gChildEntryTable[count++]=3Dobj
			obj.children.tags("TABLE").item(0).style.borderColor=3DgOtlNormalClr
		}
	}
}
function ChangeState( idx,fgColor,bgColor )
{
	obj=3Ddocument.all.item("PPTL"+idx)
	obj.style.color=3DfgColor

	obj=3Ddocument.all.item("PPTP"+idx)
	obj.style.backgroundColor=3DbgColor

	obj=3Ddocument.all.item("PPTB"+idx)
	if( obj )
		obj.style.borderLeftColor=3Dobj.style.borderBottomColor=3DbgColor
}
function ChgClr( o,clr ){ if( o.id !=3D "PPTL"+gSelected ) =
o.style.color=3Dclr }
function Over( obj ){ ChgClr(obj,gOtlActiveClr) }
function Out( obj ){ ChgClr(obj,gOtlHiliteClr) }
function ObjExists( ii ) { obj=3Ddocument.all("PPTP"+ii ); return( obj ) =
}
function GoToSld( href ){ UpdIdx(parent.GetSldNum(href)); =
parent.GoToSld( href ) }
function CancelDrag(){ =
window.event.cancelBubble=3Dtrue;window.event.returnValue=3Dfalse}

function UpdNav()
{
	txt =3D "<center>";
	if( parent.GetHrefObj( parent.gCurSld ).mOrigVis =3D=3D 1 )
		txt +=3D "Slide " + parent.GetCurSldNum() + " of " + =
parent.GetNumSlds()
	else
		txt +=3D "Hidden Slide"
	txt +=3D "</center>";
	nav_text.innerHTML =3D txt;

	if( !parent.HasPrevSld() )
		gBtnArr["nb_prev"].Enabled(0)
	else
		gBtnArr["nb_prev"].Enabled(1)

	if( !parent.HasNextSld() )
		gBtnArr["nb_next"].Enabled(0)
	else
		gBtnArr["nb_next"].Enabled(1)
	gBtnArr["nb_nts"].SetEnabled()
	gBtnArr["nb_nts"].SetFlag( parent.gHasNts )

	gBtnArr["nb_sldshw"].Enabled(1)
	gBtnArr["nb_voice"].Enabled(1)
}

function UpdOtlNav()
{
	gBtnArr["nb_otl"].SetEnabled();

	if( parent.gOtlOpen )
		gBtnArr["nb_otlTxt"].Enabled( true );
	else
		document.all.item("nb_otlTxtBorder").style.visibility =3D "hidden";
}



//-->
</SCRIPT>

<STYLE>.PTxt {
	MARGIN-TOP: 5px; PADDING-LEFT: 5px; FONT-WEIGHT: bold; WIDTH: 100%; =
POSITION: relative
}
.CTxt {
	PADDING-LEFT: 10px; WIDTH: 100%; POSITION: relative
}
.CBorder {
	BORDER-RIGHT: black 1px solid; BORDER-TOP: black 1px solid; =
PADDING-BOTTOM: 5px; BORDER-LEFT: black 1px solid; WIDTH: 100%; =
BORDER-BOTTOM: black 1px solid; POSITION: relative
}
A {
	COLOR: white; TEXT-DECORATION: none
}
.button {
	BORDER-RIGHT: buttonface 1px solid; BORDER-TOP: buttonface 1px solid; =
BORDER-LEFT: buttonface 1px solid; WIDTH: 32px; BORDER-BOTTOM: =
buttonface 1px solid; POSITION: absolute; HEIGHT: 20px
}
</STYLE>
</HEAD>
<BODY onload=3DLoad() stats=3D"1"><!-- Start of DeepMetrix (.NET) =
StatScript -->
<SCRIPT language=3Djavascript>

var DMNETdomain =3D "";
var DMNETpage =3D window.location;
var DMNETversion =3D "86";
var DMNETsendTo =3D "//campus.hws.edu/dm.gif?";
var DMNETsession;

function dmneterr(){return true;}

window.onerror=3Ddmneterr;
var s =3D new Date();

if (navigator.userAgent.indexOf('Mac') >=3D 0 && s.getTimezoneOffset() =
>=3D 720)
  s.setTime (s.getTime() - 1440*60*1000);

var dmnetURL =3D location.protocol + =
DMNETsendTo+"v=3D"+DMNETversion+"&vst=3D1";
var dmnetCookieString =3D document.cookie.toString();

if(dmnetCookieString.indexOf("_dmnid") =3D=3D -1)
  {
    DMNETsession =3D parseInt( Math.random()*1000000 ) + "_" + =
s.getTime();
    var domStr =3D "";
    if(DMNETdomain !=3D "")
    {
      domStr =3D "domain=3D"+ DMNETdomain +";";
    }
    document.cookie =3D "_dmnid=3D" + DMNETsession + ";expires=3DMon, =
31-Dec-2008 00:00:00 GMT;"+domStr+"path=3D/;";
  }
dmnetCookieString =3D document.cookie.toString();
if(dmnetCookieString.indexOf('_dmnid') =3D=3D -1)
  {
    DMNETsession =3D "";
  }
else
  {
    if(dmnetCookieString.indexOf(';') =3D=3D -1)
      dmnetCookieString =3D dmnetCookieString.replace(/_dm/g, ';_dm');

    var start =3D dmnetCookieString.indexOf("_dmnid=3D") + 7;
    var end =3D dmnetCookieString.indexOf(";",start);

    if (end =3D=3D -1)
      end =3D dmnetCookieString.length;
    DMNETsession =3D unescape(dmnetCookieString.substring(start,end));
  }
dmnetURL +=3D "&id=3D"+DMNETsession+"&url=3D"+escape(DMNETpage) + =
"&ref=3D"+escape(document.referrer)+"&lng=3D" + ((!document.all ||  =
navigator.userAgent.match('Opera')) ? navigator.language : =
navigator.userLanguage) + "&tz=3D" + (Math.round(new Date('dec 1, =
2002').getTimezoneOffset()/60)*-1);
if(screen)
  dmnetURL +=3D "&scr=3D" + escape( screen.width + "x" + screen.height + =
" " + screen.colorDepth + "bpp" );

dmnetURL +=3D "&rnd=3D" + new Date().getTime();

if(document.layers)
{
  document.write("<la"+"yer name=3D\"DMStats\" visibility=3Dhide><img =
src=3D\""+dmnetURL+"\" height=3D1 width=3D1></la"+"yer>");
}
else
{
  document.write("<di"+"v id=3D\"DMStats\" =
STYLE=3D\"position:absolute;visibility:hidden;\"><img =
src=3D\""+dmnetURL+"\" height=3D1 width=3D1></di"+"v>");
}

</SCRIPT>
<!-- End of DeepMetrix (.NET) StatScript -->
<DIV onmouseup=3DBtnOnUp() onkeypress=3D_KPH() onmousedown=3DBtnOnDown() =
id=3DNavObj=20
onmouseover=3DBtnOnOver() style=3D"DISPLAY: none; VISIBILITY: hidden"=20
onmouseout=3DBtnOnOut() onload=3D"Load()">
<TABLE style=3D"VISIBILITY: hidden; WIDTH: 70px; POSITION: absolute" =
cellSpacing=3D0=20
cellPadding=3D0 align=3Dleft>
  <TBODY>
  <TR>
    <TD noWrap>
      <DIV id=3Dnb_ntsElem=20
      style=3D"PADDING-RIGHT: 3px; PADDING-LEFT: 3px; FONT-SIZE: 9pt; =
PADDING-BOTTOM: 3px; COLOR: buttontext; PADDING-TOP: 3px; FONT-FAMILY: =
Arial; POSITION: relative"=20
      align=3Dcenter><IMG id=3Dnotes_flag style=3D"DISPLAY: none" =
src=3D""=20
      border=3D0><SPAN style=3D"mso-spacerun: yes">&nbsp; =
</SPAN>Notes</DIV>
      <DIV id=3Dnb_nts title=3D"Show/Hide Notes"=20
      style=3D"LEFT: 0%; WIDTH: 100%; POSITION: absolute; TOP: 0%; =
HEIGHT: 100%"></DIV></TD></TR></TBODY></TABLE>
<TABLE style=3D"POSITION: relative" cellSpacing=3D0 cellPadding=3D0 =
align=3Dright>
  <TBODY>
  <TR>
    <TD>
      <DIV id=3Dnb_sldshwBorder=20
      style=3D"LEFT: -20px; WIDTH: 20px; POSITION: absolute; HEIGHT: =
20px">
      <DIV style=3D"CLIP: rect(0px 18px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_sldshw title=3D"Full Screen Slide Show"=20
      style=3D"LEFT: -254px; POSITION: relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV></TD>
    <TD>
      <DIV id=3Dnb_voiceBorder=20
      style=3D"DISPLAY: none; LEFT: -40px; WIDTH: 20px; POSITION: =
absolute; HEIGHT: 20px">
      <DIV style=3D"CLIP: rect(0px 18px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_voice title=3D"Pause/Play Narration"=20
      style=3D"LEFT: -290px; POSITION: relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV></TD></TR></TBODY></TABLE>
<TABLE style=3D"POSITION: relative" cellSpacing=3D0 cellPadding=3D0 =
align=3Dcenter>
  <TBODY>
  <TR>
    <TD noWrap>
      <DIV class=3Dbutton id=3Dnb_prevBorder style=3D"LEFT: -30px">
      <DIV style=3D"CLIP: rect(0px 30px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_prev title=3D"Previous Slide" style=3D"LEFT: 0px; =
POSITION: relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV><SPAN=20
      id=3Dnav_text=20
      style=3D"FONT-SIZE: 9pt; WIDTH: 100px; COLOR: buttontext; =
FONT-FAMILY: Arial; POSITION: relative; TOP: 3px"></SPAN>
      <DIV class=3Dbutton id=3Dnb_nextBorder>
      <DIV style=3D"CLIP: rect(0px 30px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_next title=3D"Next Slide" style=3D"LEFT: -90px; POSITION: =
relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV></TD></TR></TBODY></TABLE></DIV>
<DIV onmouseup=3DBtnOnUp() onkeypress=3D_KPH() onmousedown=3DBtnOnDown() =
id=3DOtlNavObj=20
onmouseover=3DBtnOnOver() style=3D"DISPLAY: none; VISIBILITY: hidden"=20
onmouseout=3DBtnOnOut() onload=3D"Load()">
<TABLE style=3D"WIDTH: 70px; POSITION: relative" cellSpacing=3D0 =
cellPadding=3D0=20
align=3Dleft>
  <TBODY>
  <TR>
    <TD noWrap>
      <DIV id=3Dnb_otlElem=20
      style=3D"PADDING-RIGHT: 3px; PADDING-LEFT: 3px; FONT-SIZE: 9pt; =
PADDING-BOTTOM: 3px; COLOR: buttontext; PADDING-TOP: 3px; FONT-FAMILY: =
Arial; POSITION: relative"=20
      align=3Dcenter>Outline</DIV>
      <DIV id=3Dnb_otl title=3D"Show/Hide Outline"=20
      style=3D"LEFT: 0%; WIDTH: 100%; POSITION: absolute; TOP: 0%; =
HEIGHT: 100%"></DIV></TD></TR></TBODY></TABLE>
<TABLE style=3D"POSITION: relative" cellSpacing=3D0 cellPadding=3D0 =
align=3Dcenter>
  <TBODY>
  <TR>
    <TD>
      <DIV id=3Dnb_otlTxtBorder=20
      style=3D"BORDER-RIGHT: buttonface 1px solid; BORDER-TOP: =
buttonface 1px solid; LEFT: -18px; BORDER-LEFT: buttonface 1px solid; =
WIDTH: 24px; BORDER-BOTTOM: buttonface 1px solid; POSITION: absolute; =
HEIGHT: 20px">
      <DIV style=3D"CLIP: rect(0px 22px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_otlTxt title=3D"Expand/Collapse Outline"=20
      style=3D"LEFT: -157px; POSITION: relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV></TD></TR></TBODY></TABLE></DIV>
<DIV id=3DOtlObj style=3D"DISPLAY: none; VISIBILITY: hidden">
<TABLE style=3D"FONT-SIZE: 9pt; FONT-FAMILY: Arial" width=3D"100%">
  <TBODY>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP1><FONT size=3D2><A id=3DPPTL1 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0001.htm');">Behavioral =
Manifestations of=20
      Alcohol Ingestion</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC1 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB1 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 1 to 2 drinks (.01-.05 g/dL BAC) -- =
euphoria=20
            and perceived reduction in anxiety</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 3 to 5 drinks (.06-.10 g/dL BAC) -- =
judgement=20
            and motor coordination impaired,<SPAN=20
            style=3D"mso-spacerun: yes">&nbsp; </SPAN>sometimes =
increased=20
            aggression</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 10 to 13 drinks (.20-.25 g/dL BAC) --=20
            sedation</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With<SPAN style=3D"mso-spacerun: =
yes">&nbsp;=20
            </SPAN>0.30 g/dL BAC -- memory impairment and loss of=20
            consciousness</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With<SPAN style=3D"mso-spacerun: =
yes">&nbsp;=20
            </SPAN>0.40 to .50 g/dL BAC -- depressed respiration , coma, =

            death</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP2><FONT size=3D2><A id=3DPPTL2 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0027.htm');">What=20
      Factors Determine a Person=92s BAC?</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC2 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB2 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Number of Drinks Consumed</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Time</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Body Size and Build</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Sex</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Is Stomach Empty or Full?</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Past Drinking Experiences</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP3><FONT size=3D2><A id=3DPPTL3 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      =
href=3D"javascript:GoToSld('slide0010.htm');">Alcohol</A></FONT></DIV></T=
D></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP4><FONT size=3D2><A id=3DPPTL4 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      =
href=3D"javascript:GoToSld('slide0023.htm');">Absorption</A></FONT></DIV>=

      <DIV class=3DCTxt id=3DPPTC4 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB4 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Rate of absorption is dependent =

          on:</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>concentration gradient between gut and=20
          blood</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>surface area of contact</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>degree of vascularization</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Effect of Food on =
Absorption</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>food dilutes alcohol in the digestive=20
          system</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>fatty foods are slow to digest and slow to =
move=20
            from the stomach to the small=20
      intestine</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP5><FONT size=3D2><A id=3DPPTL5 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0025.htm');">Estimation of=20
      BAC</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP6><FONT size=3D2><A id=3DPPTL6 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0026.htm');">What if=20
      we were to continue for five drinks?</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP7><FONT size=3D2><A id=3DPPTL7 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0022.htm');">Slide=20
      7</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP8><FONT size=3D2><A id=3DPPTL8 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0011.htm');">Slide=20
      8</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP9><FONT size=3D2><A id=3DPPTL9 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0028.htm');">Metabolic=20
      Differences Between Men and Women</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC9 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB9 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Women are smaller than =
men</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Women have lower total body =
water content=20
            (49%) than men (58%) of comparable size</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Gastric ADH lower in =
women</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>virtually nonexistent in alcoholic=20
        women</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>declines in men over 50</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Fluctuations in gonadal hormone =
levels=20
            during the menstrual cycle may affect the rate of alcohol=20
            metabolism</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP10><FONT size=3D2><A id=3DPPTL10 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0029.htm');">Metabolic=20
      Differences Between Ethnic Groups</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC10 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB10 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Isoenzymes in Alcohol DH=20
        (ADH)</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Beta1 in Caucasian has Km 0.00023 =
g/dL</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Beta2 in Asian has Km 0.0043 =
g/dL</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Beta3 in 15% African Amer. has Km .165=20
          g/dL</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>50% Chinese and Japanese Asians =
have=20
            inactive mito. Aldehyde DH (ALDH) resulting in facial =
flushing,=20
            palpitations, dizziness, and=20
    nausea</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP11><FONT size=3D2><A id=3DPPTL11 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0032.htm');">Effect of=20
      Chronic Use</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC11 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB11 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Metabolic Tolerance</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>But=85.This is not the whole story=85.more =
to=20
            come</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP12><FONT size=3D2><A id=3DPPTL12 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0031.htm');">Alcohol=20
      on the Brain</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP13><FONT size=3D2><A id=3DPPTL13 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0030.htm');">Behavioral =
Manifestations of=20
      Alcohol Ingestion</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC13 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB13 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 1 to 2 drinks (.01-.05 g/dL BAC) -- =
euphoria=20
            and perceived reduction in anxiety</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 3 to 5 drinks (.06-.10 g/dL BAC) -- =
judgement=20
            and motor coordination impaired,<SPAN=20
            style=3D"mso-spacerun: yes">&nbsp; </SPAN>sometimes =
increased=20
            aggression</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 10 to 13 drinks (.20-.25 g/dL BAC) --=20
            sedation</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With<SPAN style=3D"mso-spacerun: =
yes">&nbsp;=20
            </SPAN>0.30 g/dL BAC -- memory impairment and loss of=20
            consciousness</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With<SPAN style=3D"mso-spacerun: =
yes">&nbsp;=20
            </SPAN>0.40 to .50 g/dL BAC -- depressed respiration , coma, =

            death</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP14><FONT size=3D2><A id=3DPPTL14 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0033.htm');">The=20
      Brain=92s Division of Labor</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP15><FONT size=3D2><A id=3DPPTL15 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      =
href=3D"javascript:GoToSld('slide0034.htm');">Neurons</A></FONT></DIV></T=
D></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP16><FONT size=3D2><A id=3DPPTL16 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      =
href=3D"javascript:GoToSld('slide0035.htm');">Synapse</A></FONT></DIV></T=
D></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP17><FONT size=3D2><A id=3DPPTL17 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0003.htm');">Alcohol=20
      Affects Neuro-transmitter Function in the Brain</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC17 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB17 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Potentiates GABA receptor =
function</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Inhibits Glutamate receptor =
function</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Increases Dopamine =
concentration</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Increases Seratonin =
release</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Stimulates Opiate Neuropeptide=20
        Release</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP18><FONT size=3D2><A id=3DPPTL18 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0006.htm');">Affect on=20
      Dopamine, Serotonin, and Endogenous Opiates (BAC ~ .01--.05=20
      g/dL)</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC18 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB18 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Dopamine stimulates pleasure =
centers and=20
            functions in positive reinforcement</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>alcohol increases Dopamine concentrations =
in=20
            nucleus acumbens and other reward centers</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Serotonin functions in mood, =
sleep and=20
            positive reinforcement</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2><SPAN=20
            style=3D"mso-spacerun: yes">&nbsp;</SPAN>alcoholics and =
thrill seekers=20
            have low serotonin levels and alcohol consumption ( and =
thrill=20
            activities) brings theses levels up to =
normal.</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Serotonergic drugs have reduced alcohol =
consumption=20
            by alcoholics.</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Endorphins and Enkephalins are =
natural=20
            neural peptides that bind to opiate receptors and produce =
euphoric=20
            effects.</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Endorphins and Enkephalins are released by =
the=20
            brain when exposed to alcohol</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Euphoria seems to stimulate further=20
          drinking</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP19><FONT size=3D2><A id=3DPPTL19 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0004.htm');">Affect on=20
      GABA function<BR>(BAC &gt;=3D.06 g/dL)</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC19 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB19 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>GABA is major inhibitory=20
            neurotransmitter</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Alcohol Potentiates GABA =
receptor=20
            function</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>GABA receptor is site of action =

          of</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2><SPAN=20
            style=3D"mso-spacerun: yes">&nbsp;</SPAN>sedative/anesthetic =

            barbiturate, pentobarbitol</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>sedative/anxiolytic =
benzodiazipines</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Major Site of Affects=20
        include:</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>medial septal nucleus -- controls =
=93arousal=20
            state=94</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Purkinje neurons in cerebellar cortex -- =
controls=20
            sensory and motor activity</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>RO 15-4513 overcomes motor=20
            impairment</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP20><FONT size=3D2><A id=3DPPTL20 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0005.htm');">Affect on=20
      Glutamate Function<BR><SPAN style=3D"mso-spacerun: =
yes">&nbsp;</SPAN>(BAC=20
      ~.02--.2 g/dL)</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC20 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB20 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Glutamate is major excitatory=20
            neurotransmitter</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Alcohol inhibits NMDA glutamate =
receptor=20
            function</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Impaired NMDA Glutamate =
Receptor Function=20
            Causes:</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>cognitive impairment and =
amnesia</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>inability to learn new =
information</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Alcohol parallels action of PCP =
or =93angel=20
            dust=94</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP21><FONT size=3D2><A id=3DPPTL21 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0008.htm');">Effect of=20
      Chronic Use</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC21 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB21 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Tolerance</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>changes in number and types of GABA=20
          receptors</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Increase in number of glutamate=20
        receptors</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Withdrawal</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>increased Anxiety within hours -- =
GABA</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>seizures -- Glutamate</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Dependence</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>changes in Dopamine and Seratonin function =
appear=20
            to be long =
lasting</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP22><FONT size=3D2><A id=3DPPTL22 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0043.htm');">Important=20
      Metabolic Interactions and Health =
Concerns</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP23><FONT size=3D2><A id=3DPPTL23 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0044.htm');">Slide=20
      23</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP24><FONT size=3D2><A id=3DPPTL24 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0041.htm');">Interaction with =
other=20
      Drugs</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC24 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB24 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Ethyl ester of =
Cocaine</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>potentiates cocaine =
=93high=94</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Aspirin and Cimetidine<SPAN=20
            style=3D"mso-spacerun: yes">&nbsp; </SPAN>Inhibits Gastric=20
          ADH</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Liver Drug Detoxification=20
          Impaired</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Depleted NAD impairs livers ability to =
clear other=20
            drugs</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP25><FONT size=3D2><A id=3DPPTL25 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0036.htm');">Metabolic=20
      Fates of Excess Ethanol and Acetaldehyde</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC25 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB25 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Ethyl esters of Fatty Acids and =

            Cholesterol</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>may cause heart damage, impair energy =
metabolism,=20
            disrupt cell membranes</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Protein Modification by=20
            Acetaldehyde</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>enzymes inactivated by imine =
adducts</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Ethanol can also be oxidized by =

            MEOS/Cytochrome P450</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>MEOS oxidation produced harmful free=20
          radicals</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP26><FONT size=3D2><A id=3DPPTL26 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0037.htm');">Other=20
      Metabolic Processes Affected by Alcohol =
Metabolism</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC26 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB26 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>High NADH/NAD =
ratio:</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Impaired Energy Metabolism</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Inhibits Lipid Degredation in =
Liver</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Stimulation of fat synthesis and increases =
in LDL=20
            and HDL levels</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Inhibition of oxidative steps in =
testosterone=20
            synthesis</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP27><FONT size=3D2><A id=3DPPTL27 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0042.htm');">Slide=20
      27</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP28><FONT size=3D2><A id=3DPPTL28 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0038.htm');">Alcohol-Induced =
Liver=20
      Damage</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC28 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB28 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Risk becomes signficant when =
alcohol=20
            consumption exceeds</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>6.2oz/day for men</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>1.55oz/day for women</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Caused by</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Free radical rx in fatty =
liver</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Cytokine stimulated differentiation of Ito =
cells=20
            into collagen myofibroblasts</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Increased levels of Acetaldehyde due to =
lower=20
            levels of Aldehyde=20
  dehydrogenase</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP29><FONT size=3D2><A id=3DPPTL29 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0039.htm');">Alcohol-Induced =
Immune System=20
      Impairment</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC29 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB29 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Suppresses proliferation of lymphocytes in =
blood,=20
            spleen, and thymus</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Reduced B cell antibody =
production</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Natural Killer (NK) cells have reduced=20
            activity</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP30><FONT size=3D2><A id=3DPPTL30 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0040.htm');">Alcohol-Induced =
Changes in=20
      the<BR>Cardiovascular System</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC30 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB30 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Reduced risk of CAD with =
&lt;=3D2=20
            drinks/day</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>increased HDL, inhibition of platelet=20
            activity</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>50% greater risk of =
hypertension with 3-4=20
            drinks/day</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Cardiomyopathy (weakened heart=20
            muscle)</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>impaired protein metabolism, free=20
        radicals</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Arrhythmias caused by alcohol =
effect on=20
            sinoatrial node</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Cerebral Vascular Disease=20
          (Stroke)</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>reduced platelet=20
      =
activity</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR></TBODY></TABLE>=
</DIV>
<DIV style=3D"DISPLAY: none"><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03.xml"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/preview.wmf"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master02.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/pres.xml"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound001.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound002.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound003.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound004.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound005.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound006.wav"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/slide0001.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03_background.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03_image001.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0027.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0010.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0023.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0025.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0025_image002.emz"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/oledata.mso"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0025_image003.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image004.emz"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image005.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image006.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image007.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image008.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image009.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022_image010.emz"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022_image011.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022_image012.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022_image013.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image014.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image015.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image016.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image017.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image018.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0028.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0029.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0032.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0032_image019.emz"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0032_image020.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0031.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0030.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image021.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image022.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image023.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image024.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image025.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image026.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image027.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0034.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0034_image028.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0034_image029.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0035.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0035_image030.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0035_image031.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0003.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0006.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0004.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0005.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0008.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0043.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image032.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image033.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image034.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image035.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image036.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0041.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0036.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0037.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0042.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0038.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0039.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0040.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master01.htm"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/master03_stylesheet.css"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/script.js"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/error.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/fullscreen.htm"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/frame.htm"></A><A=20
href=3D"about:blank"></A></DIV>
<SCRIPT language=3DJavaScript>=0A=
<!--=0A=
var SymRealOnLoad;=0A=
var SymRealOnUnload;=0A=
=0A=
function SymOnUnload()=0A=
{=0A=
  window.open =3D SymWinOpen;=0A=
  if(SymRealOnUnload !=3D null)=0A=
     SymRealOnUnload();=0A=
}=0A=
=0A=
function SymOnLoad()=0A=
{=0A=
  if(SymRealOnLoad !=3D null)=0A=
     SymRealOnLoad();=0A=
  window.open =3D SymRealWinOpen;=0A=
  SymRealOnUnload =3D window.onunload;=0A=
  window.onunload =3D SymOnUnload;=0A=
}=0A=
=0A=
SymRealOnLoad =3D window.onload;=0A=
window.onload =3D SymOnLoad;=0A=
=0A=
//-->=0A=
</SCRIPT>
</BODY></HTML>

------=_NextPart_000_001C_01C87611.59ACFD50
Content-Type: text/html;
	charset="iso-8859-1"
Content-Transfer-Encoding: quoted-printable
Content-Location: mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol on the Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001_files/outline.htm

<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN">
<HTML><HEAD>
<META http-equiv=3DContent-Type content=3D"text/html; =
charset=3Dwindows-1252">
<META content=3DPowerPoint.Slide name=3DProgId>
<META content=3D"MSHTML 6.00.6000.16608" name=3DGENERATOR><LINK =
id=3DMain-File=20
href=3D"/alcohol/bd295/metabbrain2001/Metabbrain2001.htm" =
rel=3DMain-File><LINK=20
href=3D"preview.wmf" rel=3DPreview>
<META content=3DNoIndex name=3DRobots>
<SCRIPT language=3DJavaScript>=0A=
<!--=0A=
=0A=
function SymError()=0A=
{=0A=
  return true;=0A=
}=0A=
=0A=
window.onerror =3D SymError;=0A=
=0A=
var SymRealWinOpen =3D window.open;=0A=
=0A=
function SymWinOpen(url, name, attributes)=0A=
{=0A=
  return (new Object());=0A=
}=0A=
=0A=
window.open =3D SymWinOpen;=0A=
=0A=
//-->=0A=
</SCRIPT>

<SCRIPT=20
src=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2001=
_files/script.js"></SCRIPT>

<SCRIPT><!--

if( !(IsWin("PPTOtl")||IsWin("PPTNav")||IsWin("PPTOtlNav")) )
{
	obj =3D document.all.item("Main-File")
	parent.location.href=3Dobj.href
}

var =
gOtlHiliteClr=3D"#FFFFFF",gOtlNormalClr=3D"#000000",gOtlActiveClr=3D"#FFF=
F00",gSelected=3D"",gTxtState=3Dfalse,gChildEntryTable=3Dnew Array()

function Load()
{
	if( IsWin("PPTOtl" ) ){ LoadOtl(); parent.gOtlLoaded=3Dtrue; return }
	if( IsWin("PPTNav" ) ){ LoadNav("NavObj",UpdNav); =
parent.gNavLoaded=3Dtrue; return }
	if( IsWin("PPTOtlNav" ) ){ LoadNav("OtlNavObj",UpdOtlNav); =
parent.gOtlNavLoaded=3Dtrue; return }
}
function Upd(){ if( IsWin("PPTNav") ) LoadNav("NavObj",UpdNav) }
function LoadNav( oId,UpdFunc )
{
	document.ondragstart=3DCancelDrag
	document.onselectstart=3DCancelDrag
	document.body.style.margin=3D2
	UpdFunc()
	obj=3Ddocument.all.item(oId)
	obj.style.display=3D"block"
	obj.style.visibility=3D"visible"
	document.bgColor=3D"threedface"
}
function LoadOtl()
{
	document.ondragstart=3DCancelDrag
	document.onselectstart=3DCancelDrag
	OtlObj.style.display=3D"block"
	OtlObj.style.visibility=3D"visible"
	if( gOtlActiveClr =3D=3D "" ) gOtlActiveClr=3Ddocument.linkColor
	if( gOtlHiliteClr =3D=3D "" ) gOtlHiliteClr=3Ddocument.fgColor
	if( gOtlNormalClr =3D=3D "" )
		gOtlNormalClr=3Ddocument.bgColor
	else
		document.bgColor=3DgOtlNormalClr =20

	InitArray()

	if( ObjExists( parent.gCurSld ) ) {
		ChangeState( parent.gCurSld,gOtlNormalClr,gOtlHiliteClr )
		gSelected=3Dparent.gCurSld
	}
	else gSelected =3D -1

	UpdOtl()
}
function UpdOtl(){ UpdIdx(parent.gCurSld) }
function UpdIdx( idx )
{
	if( gSelected !=3D idx ) {
		if( gSelected > 0 )
			ChangeState( gSelected,gOtlHiliteClr,gOtlNormalClr )

		if( ObjExists( idx ) ) {
			gSelected =3D idx
			ChangeState( gSelected,gOtlNormalClr,gOtlHiliteClr )
		}
		else gSelected =3D -1
	}

	if( gTxtState !=3D parent.gOtlTxtExp ) {
		state =3D "block"
		if( !parent.gOtlTxtExp )
			state=3D"none"

		for(ii=3D0; ii<gChildEntryTable.length; ii++) {
			obj=3DgChildEntryTable[ii];
			if( obj.id =3D=3D null ) continue;

			if( obj.id.indexOf("PPTC") >=3D 0 )
				obj.style.display=3Dstate;
		}=20
		gTxtState=3Dparent.gOtlTxtExp
		if( ObjExists( gSelected ) )
			ChangeState( gSelected,gOtlNormalClr,gOtlHiliteClr )
	}
}
function InitArray()
{
	count=3D0
	for(ii=3D0; ii<document.all.tags("DIV").length; ii++) {
		obj=3Ddocument.all.tags("DIV").item(ii)
		if( obj.id =3D=3D null ) continue

		if( obj.id.indexOf("PPTC") >=3D 0 ) {  =20
			gChildEntryTable[count++]=3Dobj
			obj.children.tags("TABLE").item(0).style.borderColor=3DgOtlNormalClr
		}
	}
}
function ChangeState( idx,fgColor,bgColor )
{
	obj=3Ddocument.all.item("PPTL"+idx)
	obj.style.color=3DfgColor

	obj=3Ddocument.all.item("PPTP"+idx)
	obj.style.backgroundColor=3DbgColor

	obj=3Ddocument.all.item("PPTB"+idx)
	if( obj )
		obj.style.borderLeftColor=3Dobj.style.borderBottomColor=3DbgColor
}
function ChgClr( o,clr ){ if( o.id !=3D "PPTL"+gSelected ) =
o.style.color=3Dclr }
function Over( obj ){ ChgClr(obj,gOtlActiveClr) }
function Out( obj ){ ChgClr(obj,gOtlHiliteClr) }
function ObjExists( ii ) { obj=3Ddocument.all("PPTP"+ii ); return( obj ) =
}
function GoToSld( href ){ UpdIdx(parent.GetSldNum(href)); =
parent.GoToSld( href ) }
function CancelDrag(){ =
window.event.cancelBubble=3Dtrue;window.event.returnValue=3Dfalse}

function UpdNav()
{
	txt =3D "<center>";
	if( parent.GetHrefObj( parent.gCurSld ).mOrigVis =3D=3D 1 )
		txt +=3D "Slide " + parent.GetCurSldNum() + " of " + =
parent.GetNumSlds()
	else
		txt +=3D "Hidden Slide"
	txt +=3D "</center>";
	nav_text.innerHTML =3D txt;

	if( !parent.HasPrevSld() )
		gBtnArr["nb_prev"].Enabled(0)
	else
		gBtnArr["nb_prev"].Enabled(1)

	if( !parent.HasNextSld() )
		gBtnArr["nb_next"].Enabled(0)
	else
		gBtnArr["nb_next"].Enabled(1)
	gBtnArr["nb_nts"].SetEnabled()
	gBtnArr["nb_nts"].SetFlag( parent.gHasNts )

	gBtnArr["nb_sldshw"].Enabled(1)
	gBtnArr["nb_voice"].Enabled(1)
}

function UpdOtlNav()
{
	gBtnArr["nb_otl"].SetEnabled();

	if( parent.gOtlOpen )
		gBtnArr["nb_otlTxt"].Enabled( true );
	else
		document.all.item("nb_otlTxtBorder").style.visibility =3D "hidden";
}



//-->
</SCRIPT>

<STYLE>.PTxt {
	MARGIN-TOP: 5px; PADDING-LEFT: 5px; FONT-WEIGHT: bold; WIDTH: 100%; =
POSITION: relative
}
.CTxt {
	PADDING-LEFT: 10px; WIDTH: 100%; POSITION: relative
}
.CBorder {
	BORDER-RIGHT: black 1px solid; BORDER-TOP: black 1px solid; =
PADDING-BOTTOM: 5px; BORDER-LEFT: black 1px solid; WIDTH: 100%; =
BORDER-BOTTOM: black 1px solid; POSITION: relative
}
A {
	COLOR: white; TEXT-DECORATION: none
}
.button {
	BORDER-RIGHT: buttonface 1px solid; BORDER-TOP: buttonface 1px solid; =
BORDER-LEFT: buttonface 1px solid; WIDTH: 32px; BORDER-BOTTOM: =
buttonface 1px solid; POSITION: absolute; HEIGHT: 20px
}
</STYLE>
</HEAD>
<BODY onload=3DLoad() stats=3D"1"><!-- Start of DeepMetrix (.NET) =
StatScript -->
<SCRIPT language=3Djavascript>

var DMNETdomain =3D "";
var DMNETpage =3D window.location;
var DMNETversion =3D "86";
var DMNETsendTo =3D "//campus.hws.edu/dm.gif?";
var DMNETsession;

function dmneterr(){return true;}

window.onerror=3Ddmneterr;
var s =3D new Date();

if (navigator.userAgent.indexOf('Mac') >=3D 0 && s.getTimezoneOffset() =
>=3D 720)
  s.setTime (s.getTime() - 1440*60*1000);

var dmnetURL =3D location.protocol + =
DMNETsendTo+"v=3D"+DMNETversion+"&vst=3D1";
var dmnetCookieString =3D document.cookie.toString();

if(dmnetCookieString.indexOf("_dmnid") =3D=3D -1)
  {
    DMNETsession =3D parseInt( Math.random()*1000000 ) + "_" + =
s.getTime();
    var domStr =3D "";
    if(DMNETdomain !=3D "")
    {
      domStr =3D "domain=3D"+ DMNETdomain +";";
    }
    document.cookie =3D "_dmnid=3D" + DMNETsession + ";expires=3DMon, =
31-Dec-2008 00:00:00 GMT;"+domStr+"path=3D/;";
  }
dmnetCookieString =3D document.cookie.toString();
if(dmnetCookieString.indexOf('_dmnid') =3D=3D -1)
  {
    DMNETsession =3D "";
  }
else
  {
    if(dmnetCookieString.indexOf(';') =3D=3D -1)
      dmnetCookieString =3D dmnetCookieString.replace(/_dm/g, ';_dm');

    var start =3D dmnetCookieString.indexOf("_dmnid=3D") + 7;
    var end =3D dmnetCookieString.indexOf(";",start);

    if (end =3D=3D -1)
      end =3D dmnetCookieString.length;
    DMNETsession =3D unescape(dmnetCookieString.substring(start,end));
  }
dmnetURL +=3D "&id=3D"+DMNETsession+"&url=3D"+escape(DMNETpage) + =
"&ref=3D"+escape(document.referrer)+"&lng=3D" + ((!document.all ||  =
navigator.userAgent.match('Opera')) ? navigator.language : =
navigator.userLanguage) + "&tz=3D" + (Math.round(new Date('dec 1, =
2002').getTimezoneOffset()/60)*-1);
if(screen)
  dmnetURL +=3D "&scr=3D" + escape( screen.width + "x" + screen.height + =
" " + screen.colorDepth + "bpp" );

dmnetURL +=3D "&rnd=3D" + new Date().getTime();

if(document.layers)
{
  document.write("<la"+"yer name=3D\"DMStats\" visibility=3Dhide><img =
src=3D\""+dmnetURL+"\" height=3D1 width=3D1></la"+"yer>");
}
else
{
  document.write("<di"+"v id=3D\"DMStats\" =
STYLE=3D\"position:absolute;visibility:hidden;\"><img =
src=3D\""+dmnetURL+"\" height=3D1 width=3D1></di"+"v>");
}

</SCRIPT>
<!-- End of DeepMetrix (.NET) StatScript -->
<DIV onmouseup=3DBtnOnUp() onkeypress=3D_KPH() onmousedown=3DBtnOnDown() =
id=3DNavObj=20
onmouseover=3DBtnOnOver() style=3D"DISPLAY: none; VISIBILITY: hidden"=20
onmouseout=3DBtnOnOut() onload=3D"Load()">
<TABLE style=3D"VISIBILITY: hidden; WIDTH: 70px; POSITION: absolute" =
cellSpacing=3D0=20
cellPadding=3D0 align=3Dleft>
  <TBODY>
  <TR>
    <TD noWrap>
      <DIV id=3Dnb_ntsElem=20
      style=3D"PADDING-RIGHT: 3px; PADDING-LEFT: 3px; FONT-SIZE: 9pt; =
PADDING-BOTTOM: 3px; COLOR: buttontext; PADDING-TOP: 3px; FONT-FAMILY: =
Arial; POSITION: relative"=20
      align=3Dcenter><IMG id=3Dnotes_flag style=3D"DISPLAY: none" =
src=3D""=20
      border=3D0><SPAN style=3D"mso-spacerun: yes">&nbsp; =
</SPAN>Notes</DIV>
      <DIV id=3Dnb_nts title=3D"Show/Hide Notes"=20
      style=3D"LEFT: 0%; WIDTH: 100%; POSITION: absolute; TOP: 0%; =
HEIGHT: 100%"></DIV></TD></TR></TBODY></TABLE>
<TABLE style=3D"POSITION: relative" cellSpacing=3D0 cellPadding=3D0 =
align=3Dright>
  <TBODY>
  <TR>
    <TD>
      <DIV id=3Dnb_sldshwBorder=20
      style=3D"LEFT: -20px; WIDTH: 20px; POSITION: absolute; HEIGHT: =
20px">
      <DIV style=3D"CLIP: rect(0px 18px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_sldshw title=3D"Full Screen Slide Show"=20
      style=3D"LEFT: -254px; POSITION: relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV></TD>
    <TD>
      <DIV id=3Dnb_voiceBorder=20
      style=3D"DISPLAY: none; LEFT: -40px; WIDTH: 20px; POSITION: =
absolute; HEIGHT: 20px">
      <DIV style=3D"CLIP: rect(0px 18px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_voice title=3D"Pause/Play Narration"=20
      style=3D"LEFT: -290px; POSITION: relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV></TD></TR></TBODY></TABLE>
<TABLE style=3D"POSITION: relative" cellSpacing=3D0 cellPadding=3D0 =
align=3Dcenter>
  <TBODY>
  <TR>
    <TD noWrap>
      <DIV class=3Dbutton id=3Dnb_prevBorder style=3D"LEFT: -30px">
      <DIV style=3D"CLIP: rect(0px 30px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_prev title=3D"Previous Slide" style=3D"LEFT: 0px; =
POSITION: relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV><SPAN=20
      id=3Dnav_text=20
      style=3D"FONT-SIZE: 9pt; WIDTH: 100px; COLOR: buttontext; =
FONT-FAMILY: Arial; POSITION: relative; TOP: 3px"></SPAN>
      <DIV class=3Dbutton id=3Dnb_nextBorder>
      <DIV style=3D"CLIP: rect(0px 30px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_next title=3D"Next Slide" style=3D"LEFT: -90px; POSITION: =
relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV></TD></TR></TBODY></TABLE></DIV>
<DIV onmouseup=3DBtnOnUp() onkeypress=3D_KPH() onmousedown=3DBtnOnDown() =
id=3DOtlNavObj=20
onmouseover=3DBtnOnOver() style=3D"DISPLAY: none; VISIBILITY: hidden"=20
onmouseout=3DBtnOnOut() onload=3D"Load()">
<TABLE style=3D"WIDTH: 70px; POSITION: relative" cellSpacing=3D0 =
cellPadding=3D0=20
align=3Dleft>
  <TBODY>
  <TR>
    <TD noWrap>
      <DIV id=3Dnb_otlElem=20
      style=3D"PADDING-RIGHT: 3px; PADDING-LEFT: 3px; FONT-SIZE: 9pt; =
PADDING-BOTTOM: 3px; COLOR: buttontext; PADDING-TOP: 3px; FONT-FAMILY: =
Arial; POSITION: relative"=20
      align=3Dcenter>Outline</DIV>
      <DIV id=3Dnb_otl title=3D"Show/Hide Outline"=20
      style=3D"LEFT: 0%; WIDTH: 100%; POSITION: absolute; TOP: 0%; =
HEIGHT: 100%"></DIV></TD></TR></TBODY></TABLE>
<TABLE style=3D"POSITION: relative" cellSpacing=3D0 cellPadding=3D0 =
align=3Dcenter>
  <TBODY>
  <TR>
    <TD>
      <DIV id=3Dnb_otlTxtBorder=20
      style=3D"BORDER-RIGHT: buttonface 1px solid; BORDER-TOP: =
buttonface 1px solid; LEFT: -18px; BORDER-LEFT: buttonface 1px solid; =
WIDTH: 24px; BORDER-BOTTOM: buttonface 1px solid; POSITION: absolute; =
HEIGHT: 20px">
      <DIV style=3D"CLIP: rect(0px 22px 18px 0px); POSITION: =
absolute"><IMG=20
      id=3Dnb_otlTxt title=3D"Expand/Collapse Outline"=20
      style=3D"LEFT: -157px; POSITION: relative"=20
      src=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of =
Alcohol on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></DIV></DIV></TD></TR></TBODY></TABLE></DIV>
<DIV id=3DOtlObj style=3D"DISPLAY: none; VISIBILITY: hidden">
<TABLE style=3D"FONT-SIZE: 9pt; FONT-FAMILY: Arial" width=3D"100%">
  <TBODY>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP1><FONT size=3D2><A id=3DPPTL1 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0001.htm');">Behavioral =
Manifestations of=20
      Alcohol Ingestion</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC1 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB1 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 1 to 2 drinks (.01-.05 g/dL BAC) -- =
euphoria=20
            and perceived reduction in anxiety</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 3 to 5 drinks (.06-.10 g/dL BAC) -- =
judgement=20
            and motor coordination impaired,<SPAN=20
            style=3D"mso-spacerun: yes">&nbsp; </SPAN>sometimes =
increased=20
            aggression</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 10 to 13 drinks (.20-.25 g/dL BAC) --=20
            sedation</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With<SPAN style=3D"mso-spacerun: =
yes">&nbsp;=20
            </SPAN>0.30 g/dL BAC -- memory impairment and loss of=20
            consciousness</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With<SPAN style=3D"mso-spacerun: =
yes">&nbsp;=20
            </SPAN>0.40 to .50 g/dL BAC -- depressed respiration , coma, =

            death</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP2><FONT size=3D2><A id=3DPPTL2 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0027.htm');">What=20
      Factors Determine a Person=92s BAC?</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC2 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB2 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Number of Drinks Consumed</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Time</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Body Size and Build</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Sex</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Is Stomach Empty or Full?</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Past Drinking Experiences</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP3><FONT size=3D2><A id=3DPPTL3 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      =
href=3D"javascript:GoToSld('slide0010.htm');">Alcohol</A></FONT></DIV></T=
D></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP4><FONT size=3D2><A id=3DPPTL4 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      =
href=3D"javascript:GoToSld('slide0023.htm');">Absorption</A></FONT></DIV>=

      <DIV class=3DCTxt id=3DPPTC4 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB4 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Rate of absorption is dependent =

          on:</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>concentration gradient between gut and=20
          blood</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>surface area of contact</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>degree of vascularization</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Effect of Food on =
Absorption</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>food dilutes alcohol in the digestive=20
          system</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>fatty foods are slow to digest and slow to =
move=20
            from the stomach to the small=20
      intestine</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP5><FONT size=3D2><A id=3DPPTL5 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0025.htm');">Estimation of=20
      BAC</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP6><FONT size=3D2><A id=3DPPTL6 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0026.htm');">What if=20
      we were to continue for five drinks?</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP7><FONT size=3D2><A id=3DPPTL7 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0022.htm');">Slide=20
      7</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP8><FONT size=3D2><A id=3DPPTL8 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0011.htm');">Slide=20
      8</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP9><FONT size=3D2><A id=3DPPTL9 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0028.htm');">Metabolic=20
      Differences Between Men and Women</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC9 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB9 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Women are smaller than =
men</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Women have lower total body =
water content=20
            (49%) than men (58%) of comparable size</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Gastric ADH lower in =
women</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>virtually nonexistent in alcoholic=20
        women</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>declines in men over 50</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Fluctuations in gonadal hormone =
levels=20
            during the menstrual cycle may affect the rate of alcohol=20
            metabolism</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP10><FONT size=3D2><A id=3DPPTL10 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0029.htm');">Metabolic=20
      Differences Between Ethnic Groups</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC10 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB10 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Isoenzymes in Alcohol DH=20
        (ADH)</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Beta1 in Caucasian has Km 0.00023 =
g/dL</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Beta2 in Asian has Km 0.0043 =
g/dL</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Beta3 in 15% African Amer. has Km .165=20
          g/dL</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>50% Chinese and Japanese Asians =
have=20
            inactive mito. Aldehyde DH (ALDH) resulting in facial =
flushing,=20
            palpitations, dizziness, and=20
    nausea</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP11><FONT size=3D2><A id=3DPPTL11 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0032.htm');">Effect of=20
      Chronic Use</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC11 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB11 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Metabolic Tolerance</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>But=85.This is not the whole story=85.more =
to=20
            come</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP12><FONT size=3D2><A id=3DPPTL12 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0031.htm');">Alcohol=20
      on the Brain</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP13><FONT size=3D2><A id=3DPPTL13 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0030.htm');">Behavioral =
Manifestations of=20
      Alcohol Ingestion</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC13 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB13 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 1 to 2 drinks (.01-.05 g/dL BAC) -- =
euphoria=20
            and perceived reduction in anxiety</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 3 to 5 drinks (.06-.10 g/dL BAC) -- =
judgement=20
            and motor coordination impaired,<SPAN=20
            style=3D"mso-spacerun: yes">&nbsp; </SPAN>sometimes =
increased=20
            aggression</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With 10 to 13 drinks (.20-.25 g/dL BAC) --=20
            sedation</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With<SPAN style=3D"mso-spacerun: =
yes">&nbsp;=20
            </SPAN>0.30 g/dL BAC -- memory impairment and loss of=20
            consciousness</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>With<SPAN style=3D"mso-spacerun: =
yes">&nbsp;=20
            </SPAN>0.40 to .50 g/dL BAC -- depressed respiration , coma, =

            death</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP14><FONT size=3D2><A id=3DPPTL14 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0033.htm');">The=20
      Brain=92s Division of Labor</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP15><FONT size=3D2><A id=3DPPTL15 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      =
href=3D"javascript:GoToSld('slide0034.htm');">Neurons</A></FONT></DIV></T=
D></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP16><FONT size=3D2><A id=3DPPTL16 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      =
href=3D"javascript:GoToSld('slide0035.htm');">Synapse</A></FONT></DIV></T=
D></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP17><FONT size=3D2><A id=3DPPTL17 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0003.htm');">Alcohol=20
      Affects Neuro-transmitter Function in the Brain</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC17 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB17 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Potentiates GABA receptor =
function</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Inhibits Glutamate receptor =
function</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Increases Dopamine =
concentration</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Increases Seratonin =
release</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Stimulates Opiate Neuropeptide=20
        Release</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP18><FONT size=3D2><A id=3DPPTL18 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0006.htm');">Affect on=20
      Dopamine, Serotonin, and Endogenous Opiates (BAC ~ .01--.05=20
      g/dL)</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC18 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB18 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Dopamine stimulates pleasure =
centers and=20
            functions in positive reinforcement</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>alcohol increases Dopamine concentrations =
in=20
            nucleus acumbens and other reward centers</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Serotonin functions in mood, =
sleep and=20
            positive reinforcement</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2><SPAN=20
            style=3D"mso-spacerun: yes">&nbsp;</SPAN>alcoholics and =
thrill seekers=20
            have low serotonin levels and alcohol consumption ( and =
thrill=20
            activities) brings theses levels up to =
normal.</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Serotonergic drugs have reduced alcohol =
consumption=20
            by alcoholics.</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Endorphins and Enkephalins are =
natural=20
            neural peptides that bind to opiate receptors and produce =
euphoric=20
            effects.</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Endorphins and Enkephalins are released by =
the=20
            brain when exposed to alcohol</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Euphoria seems to stimulate further=20
          drinking</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP19><FONT size=3D2><A id=3DPPTL19 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0004.htm');">Affect on=20
      GABA function<BR>(BAC &gt;=3D.06 g/dL)</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC19 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB19 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>GABA is major inhibitory=20
            neurotransmitter</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Alcohol Potentiates GABA =
receptor=20
            function</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>GABA receptor is site of action =

          of</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2><SPAN=20
            style=3D"mso-spacerun: yes">&nbsp;</SPAN>sedative/anesthetic =

            barbiturate, pentobarbitol</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>sedative/anxiolytic =
benzodiazipines</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Major Site of Affects=20
        include:</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>medial septal nucleus -- controls =
=93arousal=20
            state=94</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Purkinje neurons in cerebellar cortex -- =
controls=20
            sensory and motor activity</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>RO 15-4513 overcomes motor=20
            impairment</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP20><FONT size=3D2><A id=3DPPTL20 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0005.htm');">Affect on=20
      Glutamate Function<BR><SPAN style=3D"mso-spacerun: =
yes">&nbsp;</SPAN>(BAC=20
      ~.02--.2 g/dL)</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC20 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB20 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Glutamate is major excitatory=20
            neurotransmitter</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Alcohol inhibits NMDA glutamate =
receptor=20
            function</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Impaired NMDA Glutamate =
Receptor Function=20
            Causes:</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>cognitive impairment and =
amnesia</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>inability to learn new =
information</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Alcohol parallels action of PCP =
or =93angel=20
            dust=94</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP21><FONT size=3D2><A id=3DPPTL21 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0008.htm');">Effect of=20
      Chronic Use</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC21 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB21 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Tolerance</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>changes in number and types of GABA=20
          receptors</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Increase in number of glutamate=20
        receptors</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Withdrawal</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>increased Anxiety within hours -- =
GABA</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>seizures -- Glutamate</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Dependence</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>changes in Dopamine and Seratonin function =
appear=20
            to be long =
lasting</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP22><FONT size=3D2><A id=3DPPTL22 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0043.htm');">Important=20
      Metabolic Interactions and Health =
Concerns</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP23><FONT size=3D2><A id=3DPPTL23 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0044.htm');">Slide=20
      23</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP24><FONT size=3D2><A id=3DPPTL24 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0041.htm');">Interaction with =
other=20
      Drugs</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC24 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB24 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Ethyl ester of =
Cocaine</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>potentiates cocaine =
=93high=94</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Aspirin and Cimetidine<SPAN=20
            style=3D"mso-spacerun: yes">&nbsp; </SPAN>Inhibits Gastric=20
          ADH</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Liver Drug Detoxification=20
          Impaired</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Depleted NAD impairs livers ability to =
clear other=20
            drugs</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP25><FONT size=3D2><A id=3DPPTL25 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0036.htm');">Metabolic=20
      Fates of Excess Ethanol and Acetaldehyde</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC25 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB25 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Ethyl esters of Fatty Acids and =

            Cholesterol</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>may cause heart damage, impair energy =
metabolism,=20
            disrupt cell membranes</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Protein Modification by=20
            Acetaldehyde</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>enzymes inactivated by imine =
adducts</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Ethanol can also be oxidized by =

            MEOS/Cytochrome P450</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>MEOS oxidation produced harmful free=20
          radicals</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP26><FONT size=3D2><A id=3DPPTL26 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0037.htm');">Other=20
      Metabolic Processes Affected by Alcohol =
Metabolism</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC26 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB26 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>High NADH/NAD =
ratio:</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Impaired Energy Metabolism</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Inhibits Lipid Degredation in =
Liver</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Stimulation of fat synthesis and increases =
in LDL=20
            and HDL levels</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Inhibition of oxidative steps in =
testosterone=20
            synthesis</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP27><FONT size=3D2><A id=3DPPTL27 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this) =
href=3D"javascript:GoToSld('slide0042.htm');">Slide=20
      27</A></FONT></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP28><FONT size=3D2><A id=3DPPTL28 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0038.htm');">Alcohol-Induced =
Liver=20
      Damage</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC28 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB28 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Risk becomes signficant when =
alcohol=20
            consumption exceeds</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>6.2oz/day for men</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>1.55oz/day for women</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Caused by</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Free radical rx in fatty =
liver</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Cytokine stimulated differentiation of Ito =
cells=20
            into collagen myofibroblasts</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>Increased levels of Acetaldehyde due to =
lower=20
            levels of Aldehyde=20
  dehydrogenase</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP29><FONT size=3D2><A id=3DPPTL29 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0039.htm');">Alcohol-Induced =
Immune System=20
      Impairment</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC29 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB29 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Suppresses proliferation of lymphocytes in =
blood,=20
            spleen, and thymus</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Reduced B cell antibody =
production</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD><FONT size=3D2>Natural Killer (NK) cells have reduced=20
            activity</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR>
  <TR>
    <TD>
      <DIV class=3DPTxt id=3DPPTP30><FONT size=3D2><A id=3DPPTL30 =
onmouseover=3DOver(this)=20
      onmouseout=3DOut(this)=20
      href=3D"javascript:GoToSld('slide0040.htm');">Alcohol-Induced =
Changes in=20
      the<BR>Cardiovascular System</A></FONT></DIV>
      <DIV class=3DCTxt id=3DPPTC30 style=3D"DISPLAY: none">
      <TABLE class=3DCBorder id=3DPPTB30 style=3D"COLOR: white">
        <TBODY>
        <TR>
          <TD noWrap width=3D5></TD>
          <TD noWrap width=3D20></TD>
          <TD width=3D"100%"></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Reduced risk of CAD with =
&lt;=3D2=20
            drinks/day</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>increased HDL, inhibition of platelet=20
            activity</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>50% greater risk of =
hypertension with 3-4=20
            drinks/day</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Cardiomyopathy (weakened heart=20
            muscle)</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>impaired protein metabolism, free=20
        radicals</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Arrhythmias caused by alcohol =
effect on=20
            sinoatrial node</FONT></TD></TR>
        <TR>
          <TD></TD>
          <TD colSpan=3D2><FONT size=3D2>Cerebral Vascular Disease=20
          (Stroke)</FONT></TD></TR>
        <TR>
          <TD colSpan=3D2></TD>
          <TD><FONT size=3D2>reduced platelet=20
      =
activity</FONT></TD></TR></TBODY></TABLE></DIV></TD></TR></TBODY></TABLE>=
</DIV>
<DIV style=3D"DISPLAY: none"><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03.xml"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/preview.wmf"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master02.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/pres.xml"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound001.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound002.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound003.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound004.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound005.wav"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/sound006.wav"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/slide0001.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03_background.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master03_image001.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0027.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0010.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0023.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0025.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0025_image002.emz"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/oledata.mso"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0025_image003.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image004.emz"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image005.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image006.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image007.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image008.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0026_image009.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022_image010.emz"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022_image011.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022_image012.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0022_image013.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image014.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image015.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image016.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image017.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0011_image018.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0028.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0029.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0032.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0032_image019.emz"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0032_image020.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0031.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0030.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image021.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image022.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image023.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image024.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image025.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image026.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0033_image027.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0034.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0034_image028.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0034_image029.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0035.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0035_image030.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0035_image031.jpg"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0003.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0006.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0004.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0005.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0008.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0043.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image032.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image033.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image034.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image035.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0044_image036.gif"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0041.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0036.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0037.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0042.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0038.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0039.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/slide0040.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/master01.htm"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/master03_stylesheet.css"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/script.js"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/error.htm"></A><A=20
href=3D"http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain200=
1_files/fullscreen.htm"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/buttons.gif"></A><A=20
href=3D"mhtml:file://D:\Anatomy\08 ANATOMY Resources\Actions of Alcohol =
on the =
Brain.mht!http://alcohol.hws.edu/alcohol/bd295/metabbrain2001/Metabbrain2=
001_files/frame.htm"></A><A=20
href=3D"about:blank"></A></DIV>
<SCRIPT language=3DJavaScript>=0A=
<!--=0A=
var SymRealOnLoad;=0A=
var SymRealOnUnload;=0A=
=0A=
function SymOnUnload()=0A=
{=0A=
  window.open =3D SymWinOpen;=0A=
  if(SymRealOnUnload !=3D null)=0A=
     SymRealOnUnload();=0A=
}=0A=
=0A=
function SymOnLoad()=0A=
{=0A=
  if(SymRealOnLoad !=3D null)=0A=
     SymRealOnLoad();=0A=
  window.open =3D SymRealWinOpen;=0A=
  SymRealOnUnload =3D window.onunload;=0A=
  window.onunload =3D SymOnUnload;=0A=
}=0A=
=0A=
SymRealOnLoad =3D window.onload;=0A=
window.onload =3D SymOnLoad;=0A=
=0A=
//-->=0A=
</SCRIPT>
</BODY></HTML>

------=_NextPart_000_001C_01C87611.59ACFD50--